| Literature DB >> 4473824 |
Abstract
Cholesterol-5alpha,6alpha-epoxide hydrase activity was 96 percent greater in skin of hairless mice that were receiving suberythemic ultraviolet light irradiation for 15 weeks than in nonirradiated controls. This enzyme system, which metabolizes cholesterol-5alpha,6alpha-epoxide (a known carcinogen), appears to be substrateinducible and is apparently responsible for the concomitant reduction of the sterol carcinogen that occurs prior to tumor induction.Entities:
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Year: 1974 PMID： 4473824 DOI： 10.1126/science.186.4170.1216
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728