Literature DB >> 4472653

Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine.

R P McPartland, M C Wang, A Bloch, H Weinfeld.   

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Year:  1974        PMID: 4472653

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


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  17 in total

1.  Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation.

Authors:  Emmanuel Martin; Norbert Minet; Anne-Claire Boschat; Sylvia Sanquer; Steicy Sobrino; Christelle Lenoir; Jean Pierre de Villartay; Maria Leite-de-Moraes; Capucine Picard; Claire Soudais; Tim Bourne; Sophie Hambleton; Stephen M Hughes; Robert F Wynn; Tracy A Briggs; Smita Patel; Monica G Lawrence; Alain Fischer; Peter D Arkwright; Sylvain Latour
Journal:  JCI Insight       Date:  2020-03-12

2.  3-Deazauridine (NSC 126849): an interesting modulator of biochemical response.

Authors:  W J Moriconi; M Slavik; S Taylor
Journal:  Invest New Drugs       Date:  1986       Impact factor: 3.850

3.  Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.

Authors:  Jan Balzarini; Federico Gago; Wim Kulik; André B P van Kuilenburg; Anna Karlsson; Matt A Peterson; Morris J Robins
Journal:  J Biol Chem       Date:  2012-06-24       Impact factor: 5.157

4.  Immunology: When lymphocytes run out of steam.

Authors:  André Veillette; Dominique Davidson
Journal:  Nature       Date:  2014-05-28       Impact factor: 49.962

Review 5.  Purine and pyrimidine pathways as targets in Plasmodium falciparum.

Authors:  María Belén Cassera; Yong Zhang; Keith Z Hazleton; Vern L Schramm
Journal:  Curr Top Med Chem       Date:  2011       Impact factor: 3.295

6.  Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex.

Authors:  James A Endrizzi; Hanseong Kim; Paul M Anderson; Enoch P Baldwin
Journal:  Biochemistry       Date:  2005-10-18       Impact factor: 3.162

7.  Effect of deoxycytidine on the in vitro response of human leukemia cells to inhibitors of de novo pyrimidine biosynthesis.

Authors:  K Bhalla; S Grant
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

8.  The kinetics and feedback inhibition of cytidine 5'-triphosphate synthetase in wild-type and mutant Chinese hamster cells.

Authors:  J D McLaren; E H Chu
Journal:  Biochem Genet       Date:  1984-08       Impact factor: 1.890

9.  Pleiotropic mutants of Chinese hamster cells with altered cytidine 5'-triphosphate synthetase.

Authors:  E H Chu; J D McLaren; I C Li; B Lamb
Journal:  Biochem Genet       Date:  1984-08       Impact factor: 1.890

10.  Chemotherapy of L1210 and L1210/ARA-C leukemia with 5-aza-2'-deoxycytidine and 3-deazauridine.

Authors:  R L Momparler; L F Momparler
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

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