Literature DB >> 4470943

Penetration of cells by asbestos fibers.

J M Davis, R E Bolton, J Garrett.   

Abstract

Studies on the behavior of asbestos fibers within tissues have shown that the only cells that regularly contain asbestos are macrophages and their derivatives. However, these cells actively incorporate the asbestos fibers by the process of phagocytosis, and there is little evidence of direct penetration. Examination of the gut lining after prolonged asbestos ingestion has shown no evidence of dust penetration either through or between the epithelial cells. The structure and arrangement of these cells is discussed, and it is suggested that they are exceptionally well adapted to prevent penetration by any solid material.

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Year:  1974        PMID: 4470943      PMCID: PMC1475371          DOI: 10.1289/ehp.749255

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  3 in total

1.  Mortality in the chrysotile asbestos mines and mills of Quebec.

Authors:  J C McDonald; A D McDonald; G W Gibbs; J Siemiatycki; C E Rossiter
Journal:  Arch Environ Health       Date:  1971-06

2.  The pathological effects of subcutaneous injections of asbestos fibres in mice: migration of fibres to submesothelial tissues and induction of mesotheliomata.

Authors:  F J Roe; R L Carter; M A Walters; J S Harington
Journal:  Int J Cancer       Date:  1967-11-15       Impact factor: 7.396

3.  Intestinal triglyceride absorption in the rat. An electron microscopical study.

Authors:  R R Cardell; S Badenhausen; K R Porter
Journal:  J Cell Biol       Date:  1967-07       Impact factor: 10.539

  3 in total
  7 in total

1.  Pathogenesis of pulmonary fibrosis induced by chrysotile asbestos. Longitudinal light and electron microscopic studies on the rat model.

Authors:  E Fasske
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

Review 2.  Does asbestos exposure cause gastrointestinal cancer?

Authors:  D S Levine
Journal:  Dig Dis Sci       Date:  1985-12       Impact factor: 3.199

3.  Nucleic acid metabolism in the rat following short-term and prolonged ingestion of chrysotile asbestos or cigarette-smoke condensate.

Authors:  R Jacobs; M Weinzweig; K S Dodgson; R J Richards
Journal:  Br J Exp Pathol       Date:  1978-12

4.  A preliminary study of biochemical changes in the rat small intestine following long-term ingestion of chrysotile asbestos.

Authors:  R Jacobs; K S Dodgson; R J Richards
Journal:  Br J Exp Pathol       Date:  1977-10

5.  Light and electron microscope studies of the rat digestive tract following prolonged and short-term ingestion of chrysotile asbestos.

Authors:  R Jacobs; J Humphrys; K S Dodgson; R J Richards
Journal:  Br J Exp Pathol       Date:  1978-10

Review 6.  Nonpulmonary outcomes of asbestos exposure.

Authors:  Melisa Bunderson-Schelvan; Jean C Pfau; Robert Crouch; Andrij Holian
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2011       Impact factor: 6.393

7.  Asbestos and colon cancer: a weight-of-the-evidence review.

Authors:  J F Gamble
Journal:  Environ Health Perspect       Date:  1994-12       Impact factor: 9.031

  7 in total

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