Literature DB >> 447012

Cimetidine hepatitis.

J P Villeneuve, H A Warner.   

Abstract

This case of an adult with cimetidine-induced hepatitis is presented. An etiologic role for the drug was strongly suggested when the patient developed transient hepatic dysfunction after two reexposures to cimetidine, which reverted promptly on withdrawal of the drug. The temporal relation between the administration of the drug and the development of hepatic dysfunction suggests that it is a hypersensitivity type of reaction.

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Year:  1979        PMID: 447012

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  11 in total

1.  Chronic active hepatitis associated with cimetidine.

Authors:  P T Boyd; F Lepre; J D Dickey
Journal:  BMJ       Date:  1989-02-04

2.  Medical staff conference: cimetidine.

Authors:  L H Smith; B Scharschmidt
Journal:  West J Med       Date:  1979-11

Review 3.  Safety of acid-suppressing drugs.

Authors:  R A Smallwood; R G Berlin; N Castagnoli; H P Festen; C J Hawkey; S K Lam; M J Langman; P Lundborg; A Parkinson
Journal:  Dig Dis Sci       Date:  1995-02       Impact factor: 3.199

4.  Adverse effects of anti-ulcer drugs.

Authors:  D A Henry; M J Langman
Journal:  Drugs       Date:  1981-06       Impact factor: 9.546

Review 5.  Nephrotoxicity and hepatotoxicity of histamine H2 receptor antagonists.

Authors:  A A Fisher; D G Le Couteur
Journal:  Drug Saf       Date:  2001-01       Impact factor: 5.606

6.  Reversible hepatic dysfunction in association with cyclophosphamide therapy.

Authors:  D V Milford; N Butler; R Clarke; J Vaid
Journal:  Eur J Pediatr       Date:  1995-05       Impact factor: 3.183

Review 7.  Drug-induced cholestasis.

Authors:  H J Zimmerman; J H Lewis
Journal:  Med Toxicol       Date:  1987 Mar-Apr

8.  Cimetidine disposition in patients with Laennec's cirrhosis during multiple dosing therapy.

Authors:  J P Cello; S Oie
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

9.  Effect of cimetidine on portal pressure and systemic hemodynamics in patients with and without liver cirrhosis.

Authors:  N Nagasue; Y Ogawa; H Yukaya; M Okita; M Yamamoto; T Higashi
Journal:  Gastroenterol Jpn       Date:  1985-04

10.  Cimetidine-induced hepatitis. Electron microscopic observations and clinical pattern of liver injury.

Authors:  I Lorenzini; A M Jezequel; F Orlandi
Journal:  Dig Dis Sci       Date:  1981-03       Impact factor: 3.199

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