Literature DB >> 4469678

Pulsatile growth hormone secretion: suppression by hypothalamic ventromedial lesions and by long-acting somatostatin.

J B Martin, L P Renaud, P Brazeau.   

Abstract

Sequential blood samples, obtained from freely behaving, nonstressed male rats, showed a pulsatile pattern of growth hormone secretion with a mean interval between peaks of 68 minutes. The bursts of secretion were blocked by lesions of the hypothalamic ventromedial nuclei and by administration of a longacting preparation of synthetic somatostatin.

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Year:  1974        PMID： 4469678     DOI： 10.1126/science.186.4163.538

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

1.  Diurnal- and behaviour-related activity of ventromedial hypothalamic neurones in freely behaving rats.

Authors:  T Ono; K Sasaki; R Shibata
Journal:  J Physiol       Date:  1987-12       Impact factor: 5.182

2.  Feeding- and chemical-related activity of ventromedial hypothalamic neurones in freely behaving rats.

Authors:  T Ono; K Sasaki; R Shibata
Journal:  J Physiol       Date:  1987-12       Impact factor: 5.182

3.  Recombinant murine growth hormone particles are more immunogenic with intravenous than subcutaneous administration.

Authors:  Merry Christie; Raul M Torres; Ross M Kedl; Theodore W Randolph; John F Carpenter
Journal:  J Pharm Sci       Date:  2013-11-25       Impact factor: 3.534

Review 4.  Modulating mechanisms of neuroendocrine cell activity: the LHRH pulse generator.

Authors:  F J López; I J Merchenthaler; M Moretto; A Negro-Vilar
Journal:  Cell Mol Neurobiol       Date:  1998-02       Impact factor: 5.046

5.  Effects of ritanserin, a specific serotonin-S2 receptor antagonist, on the release of anterior pituitary hormones during insulin-induced hypoglycemia in normal humans.

Authors:  D Tepavcević; Z Giljević; I Aganović; M Korsić; S Halimi; E Suchanek; T Jelić; B Kozić; V Plavsić
Journal:  J Endocrinol Invest       Date:  1995-06       Impact factor: 4.256

6.  Influence of amygdala stimulation on the activity of identified tuberoinfundibular neurones in the rat hypothalamus.

Authors:  L P Renaud
Journal:  J Physiol       Date:  1976-08       Impact factor: 5.182

7.  Relationship between the three-hour-period sleep-wakefulness cycle and growth hormone secretion in the immature rat.

Authors:  M Kawakami; F Kimura; C W Tsai
Journal:  J Physiol       Date:  1984-03       Impact factor: 5.182

8.  Precipitation of insulinotropin in the presence of protamine: effect of phenol and zinc on the isophane ratio and the insulinotropin concentration in the supernatant.

Authors:  Y Kim; C A Rose
Journal:  Pharm Res       Date:  1995-09       Impact factor: 4.200

9.  Evidence for a physiological role of hypothalamic gastrin-releasing peptide to suppress growth hormone and prolactin release in the rat.

Authors:  S Kentroti; W L Dees; S M McCann
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

10.  Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase.

Authors:  M C Aguila
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205
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