Literature DB >> 4469670

Acetylcholine noise: analysis after chemical modification of receptor.

E M Landau, D Ben-Haim.   

Abstract

The elementary voltage pulses ("shot effects") produced by the action of acetylcholine molecules on the receptor were studied by analyzing the membrane voltage fluctuations ("noise") after acetylcholine application at the frog neuromuscular junction. The amplitude of these pulses was decreased after treatment with a disulfide-bond reducing agent. The shot effect may thus depend on the structure or conformation of the receptor molecule.

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Year:  1974        PMID： 4469670     DOI： 10.1126/science.185.4155.944

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

1.  Acetylcholine receptor: modification of synaptic gating mechanism after treatment with a disulfide bond reducing agent.

Authors:  D Ben-Haim; F Dreyer; K Peper
Journal:  Pflugers Arch       Date:  1975-03-22       Impact factor: 3.657

2.  Role of disulphide bonds in burst-like activity of nicotinic acetylcholine receptor channels in rat sympathetic neurones.

Authors:  V A Derkach; D E Kurenny; A I Melishchuk; A A Selyanko; V I Skok
Journal:  J Physiol       Date:  1991       Impact factor: 5.182

3.  The effects of pH and curare on the time course of end-plate currents at the neuromuscular junction of the frog.

Authors:  A Mallart; J Molgó
Journal:  J Physiol       Date:  1978-03       Impact factor: 5.182

4.  Electro-mechanical noise in atrial muscle fibres of the carp.

Authors:  S Akselrod; J Richter; E M Landau; Y Lass
Journal:  Experientia       Date:  1977-08-15

5.  Effects of dithiothreitol on end-plate currents.

Authors:  D A Terrar
Journal:  J Physiol       Date:  1978-03       Impact factor: 5.182

Review 6.  Biochemical investigations of ionic channels in excitable membranes.

Authors:  F Hucho; W Schiebler
Journal:  Mol Cell Biochem       Date:  1977-12-29       Impact factor: 3.396

7.  Changes in neuromuscular junction endplate current time constants produced by sulfhydryl reagents.

Authors:  A Steinacker; D C Zuazaga
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

8.  Voltage fluctuations at the frog sartorius motor endplate produced by a covalently attached activator.

Authors:  R N Cox; M Kawai; A Karlin; P W Brandt
Journal:  J Membr Biol       Date:  1979-12-14       Impact factor: 1.843

9.  The effect of procaine on the action of acetylcholine at the neuromuscular junction.

Authors:  B Katz; R Miledi
Journal:  J Physiol       Date:  1975-07       Impact factor: 5.182

10.  Acetylcholine noise in cultured chick myoballs: a voltage clamp analysis.

Authors:  G D Fischbach; Y Lass
Journal:  J Physiol       Date:  1978-07       Impact factor: 5.182
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