Literature DB >> 446686

Trans-4-hydroxy-3-methoxycinnamic acid (ferulic acid) inhibits the effect of androgens on the rat prostate.

T Saito, T Nohno, H Yoshida, H Yokoya.   

Abstract

Trans-4-hydroxy-3-methoxycinnamic acid (ferulic acid, FA) antagonized the effect of exogenous androgens on the ventral prostate (VP) in castrated rats as well as the effect of endogenous androgens in intact rats. FA, however, had no effect on the seminal vesicles (SV) and levator ani muscle (LAM), nor oestrogenic effect in female rats and mice. FA did not antagonize the receptor binding of testosterone nor inhibit the conversion of testosterone into 5 alpha-dihydrotestosterone (DHT).

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Year:  1979        PMID： 446686     DOI： 10.1007/bf01960405

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Weights of thymus and seminal vesicle in castrate mice as altered by intraperitoneal vs. subcutaneous injections of testosterone.

Authors:  H C BROWNING; I K HAWKINS; L M HOLMBERG
Journal:  Tex Rep Biol Med       Date:  1961

2.  Myotrophic activity of 19-nortestosterone and other steroids determined by modified levator ani muscle method.

Authors:  L G HERSHBERGER; E G SHIPLEY; R K MEYER
Journal:  Proc Soc Exp Biol Med       Date:  1953-05

3.  Studies on the regulation of the concentration of androgens and androgen receptors in nuclei of prostatic cells.

Authors:  N Bruchovsky; P S Rennie; A Vanson
Journal:  Biochim Biophys Acta       Date:  1975-06-25

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Bioassay of estrogens using the mouse uterine response.

Authors:  B L RUBIN; A S DORFMAN; L BLACK; R I DORFMAN
Journal:  Endocrinology       Date:  1951-10       Impact factor: 4.736

6.  Ultrastructural studies on prostatic involution in the rat. Mechanism of autophagy in epithelial cells, with special reference to the rough-surfaced endoplasmic reticulum.

Authors:  H J Helminen; J L Ericsson
Journal:  J Ultrastruct Res       Date:  1971-09

7.  In vitro effects of estrogens on the 4 -reduction of testosterone by rat prostate and liver preparations.

Authors:  D K Lee; J C Young; Y Tamura; D C Patterson; C E Bird; A F Clark
Journal:  Can J Biochem       Date:  1973-06

8.  Effects of estrogen and progesterone on cytoplasmic estrogen receptor and rates of protein synthesis in rat uterus.

Authors:  P B Coulson; E J Pavlik
Journal:  J Steroid Biochem       Date:  1977-03       Impact factor: 4.292

9.  The effects of Delta-androstenedione and Delta-androstenediol on castrated and ovariectomized rats.

Authors:  V Korenchevsky; M Dennison; M Eldridge
Journal:  Biochem J       Date:  1937-03       Impact factor: 3.857
  9 in total
  1 in total

1.  Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2.

Authors:  Chiranan Khantham; Wipawadee Yooin; Korawan Sringarm; Sarana Rose Sommano; Supat Jiranusornkul; Francisco David Carmona; Wutigri Nimlamool; Pensak Jantrawut; Pornchai Rachtanapun; Warintorn Ruksiriwanich
Journal:  Biology (Basel)       Date:  2021-04-11
  1 in total

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