Literature DB >> 446620

Pharmacological studies of a new analgesic, dl-erythro-1-phenyl-2-(o-chlorophenyl)-2-[4-(p-methoxybenzyl)-1-piperazinyl] ethanol dihydrochloride, in experimental animals.

H Nakamura, K Ishii, Y Yokoyama, S Motoyoshi, C Imazu, M Shimizu.   

Abstract

dl-Erythro-1-phenyl-2-(o-chlorophenyl)-2-[4-(p-methoxybenzyl)-1-piperazinyl] ethanol dihydrochloride showed orally a definite analgesic activity, without producing the significant morphine-like physical dependence liability, and its analgesic potency was about a half that of codeine and far superior to aminopyrine in experimental animals.

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Year:  1979        PMID: 446620     DOI: 10.1007/bf01964358

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  2 in total

1.  A COMPARISON OF DRUG EFFECTS UPON THE JAW JERK RESPONSE TO ELECTRICAL STIMULATION OF THE TOOTH PULP IN DOGS AND CATS.

Authors:  C L MITCHELL
Journal:  J Pharmacol Exp Ther       Date:  1964-10       Impact factor: 4.030

2.  Implantation of electrodes in the dentine of an upper canine tooth in the dog.

Authors:  M L Neat; R Peacock; R T Brittain
Journal:  Br J Pharmacol       Date:  1971-10       Impact factor: 8.739

  2 in total

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