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Literature DB >> 446614

Effects of D-alpha-aminoadipate on physiologically evoked responses of cat dorsal horn neurones.

Abstract

Microelectrophoretic administration of D-alpha-aminoadipate reversibly reduced excitatory responses of cat dorsal horn neurones evoked by iontophoretic glutamate and non-noxious peripheral stimuli but did not influence similar responses evoked by noxious peripheral stimuli or iontophoretic substance P.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1979 PMID： 446614 DOI： 10.1007/bf01964348

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

11 in total

1. D-alpha-aminoadipate, alpha, epsilon-diominopimelic acid and HA-966 as antagonists of amino acid-induced and synpatic excitation of mammalian spinal neurones in vivo.

Authors: T J Biscoe; J Davies; A Dray; R H Evans; M R Martin; J C Watkins
Journal: Brain Res Date: 1978-06-16 Impact factor: 3.252

2. Pharmacological and electrophysiological studies of morphine and enkephalin on rat supraspinal neurones and cat spinal neurones.

Authors: J Davies; A Dray
Journal: Br J Pharmacol Date: 1978-05 Impact factor: 8.739

3. D-alpha-Aminoadipate as a selective antagonist of amino acid-induced and synaptic excitation of mammalian spinal neurones.

Authors: T J Biscoe; R H Evans; A A Francis; M R Martin; J C Watkins; J Davies; A Dray
Journal: Nature Date: 1977 Dec 22-29 Impact factor: 49.962

10. Distribution of some synaptic transmitter suspects in cat spinal cord: glutamic acid, aspartic acid, gamma-aminobutyric acid, glycine and glutamine.

Authors: L T Graham; R P Shank; R Werman; M H Aprison
Journal: J Neurochem Date: 1967-04 Impact factor: 5.372

4 in total

1. The role of N-methylaspartate receptors in mediating responses of rat and cat spinal neurones to defined sensory stimuli.

Authors: P M Headley; C G Parsons; D C West
Journal: J Physiol Date: 1987-04 Impact factor: 5.182

2. Selective antagonism of amino acid-induced and synaptic excitation in the cat spinal cord.

Authors: J Davies; J C Watkins
Journal: J Physiol Date: 1979-12 Impact factor: 5.182

3. An ionophoretic study of the responses of rat caudal trigeminal nucleus neurones to non-noxious mechanical sensory stimuli.

Authors: R G Hill; T E Salt
Journal: J Physiol Date: 1982-06 Impact factor: 5.182

4. Selective antinociceptive effects of tizanidine (DS 103-282), a centrally acting muscle relaxant, on dorsal horn neurones in the feline spinal cord.

Authors: J Davies; S E Johnston
Journal: Br J Pharmacol Date: 1984-06 Impact factor: 8.739

4 in total

Effects of D-alpha-aminoadipate on physiologically evoked responses of cat dorsal horn neurones.

1. D-alpha-aminoadipate, alpha, epsilon-diominopimelic acid and HA-966 as antagonists of amino acid-induced and synpatic excitation of mammalian spinal neurones in vivo.

2. Pharmacological and electrophysiological studies of morphine and enkephalin on rat supraspinal neurones and cat spinal neurones.

3. D-alpha-Aminoadipate as a selective antagonist of amino acid-induced and synaptic excitation of mammalian spinal neurones.

4. Effect of substance P in cat dorsal horn neurones activated by noxious stimuli.

5. Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia: enkephalin and substance P.

6. Spinal interneurone excitation by conformationally restricted analogues of L-glutamic acid.

Review 7. Amino acid transmitters in the mammalian central nervous system.

8. The differential sensitivity of spinal interneurones and Renshaw cells to Kainate and N-methyl-D-aspartate.

9. The actions of certain amino acids as neuronal excitants [proceedings].

10. Distribution of some synaptic transmitter suspects in cat spinal cord: glutamic acid, aspartic acid, gamma-aminobutyric acid, glycine and glutamine.

1. The role of N-methylaspartate receptors in mediating responses of rat and cat spinal neurones to defined sensory stimuli.

2. Selective antagonism of amino acid-induced and synaptic excitation in the cat spinal cord.

3. An ionophoretic study of the responses of rat caudal trigeminal nucleus neurones to non-noxious mechanical sensory stimuli.

4. Selective antinociceptive effects of tizanidine (DS 103-282), a centrally acting muscle relaxant, on dorsal horn neurones in the feline spinal cord.