Literature DB >> 446582

Suppressive effect of interferon on erythroid cell proliferation.

J A Ortega, A Ma, N A Shore, P P Dukes, T C Merigan.   

Abstract

The effect of interferon on mouse and human in vitro erythropoiesis was investigated using the mouse marrow CFU-E and the human blood BFU-E systems, respectively. Homologous interferons were found to have a marked inhibitory effect on mouse CFU-E and human BFU-E proliferation. This inhibitory effect was dose related and independent of the erythropoietin concentration used. The effective concentration of human interferon was within the range observed in humans following viral infections. It is suggested that interferon may play a role in the mechanism of the acute erythroblastopenic crisis observed at times in patients with chronic anemia following viral infections.

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Year:  1979        PMID： 446582

Source DB:  PubMed          Journal:  Exp Hematol        ISSN： 0301-472X            Impact factor:   3.084


  8 in total

1.  Side effects of interferon-alpha therapy.

Authors:  Stefan Sleijfer; Marjolein Bannink; Arthur R Van Gool; Wim H J Kruit; Gerrit Stoter
Journal:  Pharm World Sci       Date:  2005-12

2.  Suppression of normal human erythropoiesis by gamma interferon in vitro. Role of monocytes and T lymphocytes.

Authors:  S W Mamus; S Beck-Schroeder; E D Zanjani
Journal:  J Clin Invest       Date:  1985-05       Impact factor: 14.808

Review 3.  The function of lymphocytes in normal and suppressed hematopoiesis.

Authors:  N Zoumbos; P Gascon; N Young
Journal:  Blut       Date:  1984-01

4.  Chronic exposure to IFNα drives medullar lymphopoiesis towards T-cell differentiation in mice.

Authors:  Marianna Di Scala; Irene Gil-Fariña; Lucia Vanrell; Rodrigo Sánchez-Bayona; Diego Alignani; Cristina Olagüe; Africa Vales; Pedro Berraondo; Jesús Prieto; Gloria González-Aseguinolaza
Journal:  Haematologica       Date:  2015-02-24       Impact factor: 9.941

5.  Interferon-alfa corrects thrombocytosis in patients with myeloproliferative disorders.

Authors:  H Ludwig; W Linkesch; H Gisslinger; E Fritz; H Sinzinger; T Radaszkiewicz; A Chott; R Flener; M Micksche
Journal:  Cancer Immunol Immunother       Date:  1987       Impact factor: 6.968

6.  Characterization of a virus that causes transient aplastic crisis.

Authors:  N S Young; P P Mortimer; J G Moore; R K Humphries
Journal:  J Clin Invest       Date:  1984-01       Impact factor: 14.808

7.  Effects of tilorone on hemopoietic stem cells and on the development of Friend leukemia.

Authors:  H J Seidel; U Opitz; L Kreja
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

Review 8.  The 2-5A system: modulation of viral and cellular processes through acceleration of RNA degradation.

Authors:  M R Player; P F Torrence
Journal:  Pharmacol Ther       Date:  1998-05       Impact factor: 12.310
  8 in total

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