Literature DB >> 4464856

The identification of 3,3', 5,5',-tetraiodothyroformic acid within the rat liver.

D B Ramsden, A M Lawson, P J Raw, R Hoffenberg.   

Abstract

Homogenized rat livers were extracted with organic solvents and the extracts converted into more readily volatile derivatives (trimethylsilylmethyl esters and permethyl esters). Combined g.l.c.-mass-spectrometric analysis identified the presence of tetraiodothyroformate. It is postulated that mitochondrial beta-oxidation of tetraiodothyropyruvate results in the formation of this apparently undescribed metabolite.

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Year:  1974        PMID： 4464856      PMCID： PMC1168350          DOI： 10.1042/bj1430047

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

1.  The identification of the acetic acid analogues of thyroxine and tri-iodothyronine in mammalian tissues.

Authors:  V A GALTON; R PITT-RIVERS
Journal:  Biochem J       Date:  1959-06       Impact factor: 3.857

2.  [Biliary excretion of sulfaconjugated 3,3',5-triiodothyroacetic acid after administration in rats].

Authors:  J ROCHE; R MICHEL
Journal:  C R Hebd Seances Acad Sci       Date:  1957-08-05

3.  Enterohepatic circulation of thyroxine in humans.

Authors:  N B MYANT
Journal:  Clin Sci       Date:  1956-11       Impact factor: 6.124

4.  Metabolism of L-thyroxine and L-3:5:3'-triiodothyronine by brain tissue preparations.

Authors:  J E RALL; R W RAWSON; J R TATA
Journal:  Endocrinology       Date:  1957-01       Impact factor: 4.736

5.  [The nature of iodinated compounds excreted by liver and kidneys after administration of L-thyroxin and L-3,5,3'-triiodothyronine].

Authors:  J ROCHE; R MICHEL; J TATA
Journal:  Biochim Biophys Acta       Date:  1954-12

6.  The in-vitro deiodination of thyroxine and triiodothyronine.

Authors:  N F MACLAGAN; W E SPROTT
Journal:  Lancet       Date:  1954-08-21       Impact factor: 79.321

7.  I131-labeled 1-thyroxine. II. Nature of the excretion product in bile.

Authors:  A TAUROG; F N BRIGGS; I L CHAIKOFF
Journal:  J Biol Chem       Date:  1952-02       Impact factor: 5.157

8.  GLC assay of sodium thyroxine.

Authors:  R O Zimmerer; L T Grady
Journal:  J Pharm Sci       Date:  1971-03       Impact factor: 3.534

9.  Gas chromatography of the trimethylsilyl derivatives of iodotyrosines and iodothyronines.

Authors:  N M Alexander; R Scheig
Journal:  Anal Biochem       Date:  1968-02       Impact factor: 3.365

10.  [Biliary excretion of a sulfoconjugate of 3,5,3'-triiodo-L-thyronine (T-3) after administration of this hormone to the rat].

Authors:  J ROCHE; R MICHEL; O MICHEL; N ETLING
Journal:  C R Hebd Seances Acad Sci       Date:  1957-09-23
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