Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Carnitine and trimethylaminobutyrate synthesis in rat tissues.

Literature DB >> 4464847

Carnitine and trimethylaminobutyrate synthesis in rat tissues.

Abstract

Liver and testis slices convert 6-N-trimethyl-lysine into 4-N-trimethylaminobutyrate and carnitine. Adipose, skeletal muscle, heart, or kidney tissues metabolize trimethyl-lysine into trimethylaminobutyrate but not into carnitine. Trimethylaminobutyrate hydroxylation, forming carnitine, occurs in liver and to a minor degree in testis. Liver is the primary site of carnitine biosynthesis in the rat.

Entities: Chemical Species

Mesh：

Substances：
Aminobutyrates
Carnitine

Year: 1974 PMID： 4464847 PMCID： PMC1168338 DOI： 10.1042/bj1420699

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

9 in total

1. ENZYMOLOGICAL DETERMINATION OF FREE CARNITINE CONCENTRATIONS IN RAT TISSUES.

Authors: N R MARQUIS; I B FRITZ
Journal: J Lipid Res Date: 1964-04 Impact factor: 5.922

2. Carnitine.

Authors: G FRAENKEL; S FRIEDMAN
Journal: Vitam Horm Date: 1957 Impact factor: 3.421

3. Hydroxylation of gamma-butyrobetaine to carnitine in rat liver.

Authors: G Lindstedt
Journal: Biochemistry Date: 1967-05 Impact factor: 3.162

4. Role of lysine and -N-trimethyllysine in carnitine biosynthesis. I. Studies in Neurospora crassa.

Authors: D W Horne; H P Broquist
Journal: J Biol Chem Date: 1973-03-25 Impact factor: 5.157

5. Protein methylation.

Authors: W K Paik; S Kim
Journal: Science Date: 1971-10-08 Impact factor: 47.728

6. Age-dependency of various protein methylases.

Authors: W K Paik; H W Lee; D Lawson
Journal: Exp Gerontol Date: 1971-08 Impact factor: 4.032

7. Carnitine and derivatives in rat tissues.

Authors: D J Pearson; P K Tubbs
Journal: Biochem J Date: 1967-12 Impact factor: 3.857

8. Biosynthesis of carnitine and 4-N-trimethylaminobutyrate from 6-N-trimethyl-lysine.

Authors: R A Cox; C L Hoppel
Journal: Biochem J Date: 1973-12 Impact factor: 3.857

9. Biosynthesis of carnitine and 4-N-trimethylaminobutyrate from lysine.

Authors: R A Cox; C L Hoppel
Journal: Biochem J Date: 1973-12 Impact factor: 3.857

9 in total

7 in total

Review 1. Carnitine biosynthesis in mammals.

Authors: Frédéric M Vaz; Ronald J A Wanders
Journal: Biochem J Date: 2002-02-01 Impact factor: 3.857

Carnitine and trimethylaminobutyrate synthesis in rat tissues.

1. ENZYMOLOGICAL DETERMINATION OF FREE CARNITINE CONCENTRATIONS IN RAT TISSUES.

2. Carnitine.

3. Hydroxylation of gamma-butyrobetaine to carnitine in rat liver.

4. Role of lysine and -N-trimethyllysine in carnitine biosynthesis. I. Studies in Neurospora crassa.

5. Protein methylation.

6. Age-dependency of various protein methylases.

7. Carnitine and derivatives in rat tissues.

8. Biosynthesis of carnitine and 4-N-trimethylaminobutyrate from 6-N-trimethyl-lysine.

9. Biosynthesis of carnitine and 4-N-trimethylaminobutyrate from lysine.

Review 1. Carnitine biosynthesis in mammals.

2. gamma-butyrobetaine in tissues and serum of fed and starved rats determined by an enzymic radioisotopic procedure.

3. Variation in tissue carnitine concentrations with age and sex in the rat.

4. Lipid intermediates in chronically volume-overloaded rat hearts. Effect of diffuse ischemia.

5. N6-Trimethyl-lysine metabolism. 3-Hydroxy-N6-trimethyl-lysine and carnitine biosynthesis.

6. Carnitine biosynthesis. Hydroxylation of N6-trimethyl-lysine to 3-hydroxy-N6-trimethyl-lysine.

7. The Effects of Streptozotocin-Induced Diabetes and Insulin Treatment on Carnitine Biosynthesis and Renal Excretion.