Literature DB >> 446465

Effect of toxaphene on pyruvic and lactic acid levels in the rat.

D B Peakall.   

Abstract

Rats were given a single dose of toxaphene (120 mg/kg equilavent to 1/2 LD50) and sacrificed at 1, 5, and 15 days. No alterations of levels of pyruvic or lactic acid in blood plasma were observed. In a second experiment, rats were given 2.4 mg/kg daily and sacrificed at 1, 3, and 6 months, and again no alterations of pyruvic or lactic acid levels were found. It is concluded that observed alterations of the activity of lactic acid dehydrogenase induced by toxaphene do not give rise to physiological changes in unstressed rats.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 446465      PMCID： PMC1637716          DOI： 10.1289/ehp.793097

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN： 0091-6765            Impact factor:   9.031


  4 in total

1.  The influence of carathane and toxaphene on the activity of some enzymes in rat's tissues in the studies in vivo.

Authors:  H Gertig; W Nowaczyk
Journal:  Pol J Pharmacol Pharm       Date:  1975 Jul-Aug

2.  An enzymatic fluorimetric micromethod for the determination of acetoacetate, -hydroxybutyrate, pyruvate and lactate.

Authors:  C Olsen
Journal:  Clin Chim Acta       Date:  1971-07       Impact factor: 3.786

3.  Lactate and pyruvate in the brain of rats during changes in acid-base balance.

Authors:  I Leusen; E Lacroix; G Demeester
Journal:  Arch Int Physiol Biochim       Date:  1967-04

4.  Acute dieldrin toxicity: biochemical changes in the blood.

Authors:  S C Bhatia; S C Sharma; T A Venkitasubramanian
Journal:  Arch Environ Health       Date:  1972-05
  4 in total
  1 in total

1.  Soviet-American cooperation in environmental health science.

Authors:  P E Schambra; D P Rall; G I Sidorenko; M A Pinigin; N N Litvinov
Journal:  Environ Health Perspect       Date:  1979-06       Impact factor: 9.031
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.