Literature DB >> 446432

Anticonvulsant properties of betaine.

W J Freed, J C Gillin, R J Wyatt.   

Abstract

It has been shown previously that convulsions induced by homocysteine are blocked by betaine. In the present study, betaine was found to block the induction of convulsions by electroconvulsive shock and by pentylenetetrazol at least at effectively as it blocked convulsions induced by homocysteine. Thus, betaine has a general anticonvulsant action, the reason for which is unknown.

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Year:  1979        PMID： 446432     DOI： 10.1111/j.1528-1157.1979.tb04797.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN： 0013-9580            Impact factor:   5.864


  4 in total

1.  Aldehyde dehydrogenase from adult human brain that dehydrogenates gamma-aminobutyraldehyde: purification, characterization, cloning and distribution.

Authors:  A Kikonyogo; R Pietruszko
Journal:  Biochem J       Date:  1996-05-15       Impact factor: 3.857

2.  Hippocampal betaine/GABA transporter mRNA expression is not regulated by inflammation or dehydration post-status epilepticus.

Authors:  Nicole M Rowley; Misty D Smith; John G Lamb; Arne Schousboe; H Steve White
Journal:  J Neurochem       Date:  2011-02-09       Impact factor: 5.372

Review 3.  The betaine/GABA transporter and betaine: roles in brain, kidney, and liver.

Authors:  Stephen A Kempson; Yun Zhou; Niels C Danbolt
Journal:  Front Physiol       Date:  2014-04-24       Impact factor: 4.566

4.  Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans.

Authors:  Aude S Peden; Patrick Mac; You-Jun Fei; Cecilia Castro; Guoliang Jiang; Kenneth J Murfitt; Eric A Miska; Julian L Griffin; Vadivel Ganapathy; Erik M Jorgensen
Journal:  Nat Neurosci       Date:  2013-11-10       Impact factor: 24.884
  4 in total

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