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Literature DB >> 4455556

Dosage compensation of genes on the left and right arms of the X chromosome of Drosophila pseudoobscura and Drosophila willistoni.

Abstract

We have investigated the occurrence of dosage compensation in D. willistoni and D. pseudoobscura, two species whose X chromosome is metacentric with one arm homologous to the X and the other homologous to the left arm of chromosome 3 of D. melanogaster. Crude extracts were assayed for isocitrate dehydrogenase (XR), glucose-6-phosphate dehydrogenase (XL?), 6-phosphogluconate dehydrogenase (XL?), and alpha-glycerophosphate dehydrogenase (chromosome 2) in D. willistoni, and for esterase-5 (XR), glucose-6-phosphate dehydrogenase (XL?), 6-phosphogluconate dehydrogenase (XL?) and amylase (chromosome 3) in D. pseudoobscura. Our results indicate that a mechanism for dosage compensation is operative in both arms of the X chromosome of these two species.

Entities: Gene Species

Mesh：

Substances：

Year: 1974 PMID： 4455556 PMCID： PMC1213241

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

7 in total

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13 in total

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