Literature DB >> 445484

Age-related decrease of ultraviolet light-induced DNA repair synthesis in human peripheral leukocytes.

B Lambert, U Ringborg, L Skoog.   

Abstract

The capacity for ultraviolet light-induced DNA repair synthesis, studied in peripheral leukocytes from 58 healthy subjects 13 to 94 years old, was found to vary greatly between individuals. A negative, statistically significant correlation was obtained between age and this synthesis, indicating a decrease in repair capacity with age. An age-related decrease in DNA repair may increase the susceptibility of cells to agents causing DNA damage, i.e. carcinogens and certain cytostatic drugs.

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Year:  1979        PMID： 445484

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  11 in total

1.  Cytogenetic analysis of blood lymphocytes from X-ray radiographers.

Authors:  E K Shubber; A W al-Shaikhly
Journal:  Int Arch Occup Environ Health       Date:  1989       Impact factor: 3.015

2.  Epidemiology of ultraviolet-DNA repair capacity and human cancer.

Authors:  L Grossman
Journal:  Environ Health Perspect       Date:  1997-06       Impact factor: 9.031

3.  DNA repair and aging in basal cell carcinoma: a molecular epidemiology study.

Authors:  Q Wei; G M Matanoski; E R Farmer; M A Hedayati; L Grossman
Journal:  Proc Natl Acad Sci U S A       Date:  1993-02-15       Impact factor: 11.205

4.  Reduced DNA repair capacity for removing tobacco carcinogen-induced DNA adducts contributes to risk of head and neck cancer but not tumor characteristics.

Authors:  Li-E Wang; Zhibin Hu; Erich M Sturgis; Margaret R Spitz; Sara S Strom; Christopher I Amos; Zhaozheng Guo; Yawei Qiao; Ann Marie Gillenwater; Jeffrey N Myers; Gary L Clayman; Randal S Weber; Adel K El-Naggar; Li Mao; Scott M Lippman; Waun Ki Hong; Qingyi Wei
Journal:  Clin Cancer Res       Date:  2010-01-12       Impact factor: 12.531

5.  Influence of age, sex and strain on the in vitro induction of unscheduled DNA synthesis in rat hepatocyte primary cultures.

Authors:  G S Probst; L E Hill
Journal:  Cell Biol Toxicol       Date:  1987-06       Impact factor: 6.691

6.  Cells from long-lived mutant mice exhibit enhanced repair of ultraviolet lesions.

Authors:  Adam B Salmon; Mats Ljungman; Richard A Miller
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2008-03       Impact factor: 6.053

7.  Heat-labile glucose-6-phosphate dehydrogenase in cultured fibroblasts from patients with De Sanctis-Cacchione Syndrome.

Authors:  N Okada; Y Kitano
Journal:  Arch Dermatol Res       Date:  1981       Impact factor: 3.017

Review 8.  Differentiation of the mammary gland and susceptibility to carcinogenesis.

Authors:  J Russo; L K Tay; I H Russo
Journal:  Breast Cancer Res Treat       Date:  1982       Impact factor: 4.872

Review 9.  Age Is Relative-Impact of Donor Age on Induced Pluripotent Stem Cell-Derived Cell Functionality.

Authors:  Elisabeth Tamara Strässler; Katriina Aalto-Setälä; Mostafa Kiamehr; Ulf Landmesser; Nicolle Kränkel
Journal:  Front Cardiovasc Med       Date:  2018-01-25

10.  An optimized comet-based in vitro DNA repair assay to assess base and nucleotide excision repair activity.

Authors:  Sona Vodenkova; Amaya Azqueta; Andrew Collins; Maria Dusinska; Isabel Gaivão; Peter Møller; Alena Opattova; Pavel Vodicka; Roger W L Godschalk; Sabine A S Langie
Journal:  Nat Protoc       Date:  2020-11-16       Impact factor: 13.491
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