Literature DB >> 4451632

Formation of N-nitrosopyrrolidine in a dog's stomach.

T S Mysliwy, E L Wick, M C Archer, R C Shank, P M Newberne.   

Abstract

The formation of N-nitrosopyrrolidine from sodium nitrite and pyrrolidine in vivo in a dog's stomach is demonstrated. The rate of formation of nitrosopyrrolidine is shown to be subject to pronounced catalytic effects. Nitrosopyrrolidine is also shown to disappear rapidly from the stomach, probably due to absorption.

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Year:  1974        PMID： 4451632      PMCID： PMC2009216          DOI： 10.1038/bjc.1974.192

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  10 in total

1.  Induction of liver and lung tumours in rats by the simultaneous administration of sodium nitrite and morpholine.

Authors:  P M Ndwberne; R C Shank
Journal:  Food Cosmet Toxicol       Date:  1973-10

2.  Nitrosamine studies: neoplasms of liver and genital mesothelium in nitrosopyrrolidine-treated MRC rats.

Authors:  M Greenblatt; W Lijinsky
Journal:  J Natl Cancer Inst       Date:  1972-06       Impact factor: 13.506

3.  Formation of N-nitrosopiperidine from piperidine and sodium nitrite in the stomach and the isolated intestinal loop of the rat.

Authors:  B S Alam; I B Saporoschetz; S S Epstein
Journal:  Nature       Date:  1971-07-09       Impact factor: 49.962

Review 4.  Carcinogenic nitroso compounds.

Authors:  P N Magee; J M Barnes
Journal:  Adv Cancer Res       Date:  1967       Impact factor: 6.242

5.  Factors influencing the rate of formation of nitrosomorpholine from morpholine and nitrite: acceleration by thiocyanate and other anions.

Authors:  T Y Fan; S R Tannenbaum
Journal:  J Agric Food Chem       Date:  1973 Mar-Apr       Impact factor: 5.279

6.  The effect of pH on dimethylnitrosamine formation in human gastric juice.

Authors:  R P Lane; M E Bailey
Journal:  Food Cosmet Toxicol       Date:  1973-10

7.  Rapid gastric absorption of sodium nitrite in mice.

Authors:  M A Friedman; E J Greene; S S Epstein
Journal:  J Pharm Sci       Date:  1972-09       Impact factor: 3.534

8.  [Bacterial reduction of nitrate in the human stomach as a cause of a nitrosamine formation].

Authors:  J Sander; F Seif
Journal:  Arzneimittelforschung       Date:  1969-07

9.  Nitrosamines as environmental carcinogens.

Authors:  W Lijinsky; S S Epstein
Journal:  Nature       Date:  1970-01-03       Impact factor: 49.962

10.  [Can nitrites in the human diet be the cause of cancerogenesis through formation of nitrosamines?].

Authors:  J Sander
Journal:  Arch Hyg Bakteriol       Date:  1967-05
  10 in total
  1 in total

1.  Effect of diet on DEN clearance and carcinogenesis in rats.

Authors:  A E Rogers; J S Wishnok; M C Archer
Journal:  Br J Cancer       Date:  1975-06       Impact factor: 7.640
  1 in total

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