Literature DB >> 4451626

Cellular immunity, peripheral blood lymphocyte count and pathological staging of tumours in the gastrointestinal tract.

G Bone, I Lauder.   

Abstract

The peripheral blood lymphocyte count has been measured in 74 cases of histologically proven carcinoma of the gastrointestinal tract. The count has been correlated with the pathological stage of tumour spread and the patient's delayed hypersensitivity response to 2.4 dinitrochlorobenzene (DNCB). A statistically significant correlation was found between the peripheral blood lymphocyte count and the response to DNCB. There was linear association between the extent of spread of the tumours and the lymphocyte count. Those patients with low peripheral blood lymphocyte counts tended to have more advanced tumours and a poor response to DNCB. The possible causes of this lymphopenia are discussed.

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Year:  1974        PMID： 4451626      PMCID： PMC2009205          DOI： 10.1038/bjc.1974.184

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  20 in total

Review 1.  Immunotherapy of cancer. Present status and future potential.

Authors:  D L Morton
Journal:  Cancer       Date:  1972-12       Impact factor: 6.860

2.  Immunologically competent cells in the treatment of malignant disease.

Authors:  M O Symes; A G Riddell; E J Immelman; J Terblanche
Journal:  Lancet       Date:  1968-05-18       Impact factor: 79.321

3.  Immunologic alterations in bronchogenic cancer. Sequential study.

Authors:  M J Krant; G Manskopf; C S Brandrup; M A Madoff
Journal:  Cancer       Date:  1968-04       Impact factor: 6.860

4.  Evidence for immune reactions to neuroblastoma and future possibilities for investigation.

Authors:  A H Bill; A Morgan
Journal:  J Pediatr Surg       Date:  1970-04       Impact factor: 2.545

5.  Five-year cancer cure: relation to total amount of peripheral lymphocytes and neutrophils.

Authors:  A Riesco
Journal:  Cancer       Date:  1970-01       Impact factor: 6.860

6.  Impaired immunologic reactivity and recurrence following cancer surgery.

Authors:  F R Eilber; D L Morton
Journal:  Cancer       Date:  1970-02       Impact factor: 6.860

7.  Colony inhibition studies on blocking and non-blocking serum effects on cellular immunity to Moloney sarcomas.

Authors:  I Hellström; K E Hellström
Journal:  Int J Cancer       Date:  1970-03-15       Impact factor: 7.396

8.  Skin reactivity in patients with cancer. Impaired delayed hypersensitivity or faulty inflammatory response?

Authors:  M W Johnson; H I Maibach; S E Salmon
Journal:  N Engl J Med       Date:  1971-06-03       Impact factor: 91.245

9.  A histochemical analysis of mononuclear cell infiltrates of the skin. II. Delayed hypersensitivity in the human.

Authors:  J L Turk; E J Rudner; C J Heather
Journal:  Int Arch Allergy Appl Immunol       Date:  1966

10.  The significance of lymphocytic infiltration in neuroblastoma.

Authors:  I Lauder; W Aherne
Journal:  Br J Cancer       Date:  1972-08       Impact factor: 7.640
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  6 in total

1.  Cellular immunity in cancer: comparison of delayed hypersensitivity skin tests in three common cancers.

Authors:  P M Bolton; A M Mander; J M Davidson; S L James; R G Newcombe; L E Hughes
Journal:  Br Med J       Date:  1975-07-05

2.  Lymphopenia during chemoradiation-foe or friend.

Authors:  Vijay M Patil; Gunjesh Kumar Singh; Vanita Noronha; Amit Joshi; Nandini Menon; Sarbani Ghosh Lashkar; Vijayalakshmi Mathrudev; Kavita Nawale Satam; Sadaf Abdulazeez Mukadam; Kumar Prabhash
Journal:  Ecancermedicalscience       Date:  2020-09-24

3.  Colonic carcinoma: clinicopathological correlation with immunoreactivity.

Authors:  E Pihl; E S Hughes; A P Nind; R C Nairn
Journal:  Br Med J       Date:  1975-09-27

Review 4.  Tumour immunology and the gut.

Authors:  K C Calman
Journal:  Gut       Date:  1975-06       Impact factor: 23.059

5.  Secretory immunoglobulins in colonic neoplasms.

Authors:  P Weisz-Carrington; M E Poger; M E Lamm
Journal:  Am J Pathol       Date:  1976-11       Impact factor: 4.307

Review 6.  Lymphopenia in Cancer Patients and its Effects on Response to Immunotherapy: an opportunity for combination with Cytokines?

Authors:  Christine Ménétrier-Caux; Isabelle Ray-Coquard; Jean-Yves Blay; Christophe Caux
Journal:  J Immunother Cancer       Date:  2019-03-28       Impact factor: 13.751
  6 in total

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