| Literature DB >> 4451380 |
J R Valenta, C J DiCuollo, L R Fare, J F Pagano.
Abstract
The anthelmintic agent methyl 5(6)-butyl-2-benzimidazolecarbamate (Parbendazole) was transformed to two of its animal metabolites, methyl 5(6)-(4-hydroxybutyl)-2-benzimidazolecarbamate and methyl 5(6)-3-(carboxypropyl)-2-benzimidazolecarbamate, by the filamentous fungus Cunninghamella bainieri ATCC 9244. The transformation pathway was shown to be through the 4-hydroxybutyl product to the 3-carboxypropyl product. The reaction favored accumulation of the latter product.Entities:
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Year: 1974 PMID： 4451380 PMCID： PMC186870 DOI： 10.1128/am.28.6.995-998.1974
Source DB: PubMed Journal: Appl Microbiol ISSN： 0003-6919