Literature DB >> 4447864

Some effects of dipyridamole, hexobendine and lidoflazine on inhibitory processes in rabbit duodenum.

M E Hulme, A H Weston.   

Abstract

Some of the effects of dipyridamole, hexobendine and lidoflazine on mechanical responses in rabbit duodenum have been investigated. In concentrations known to inhibit tissue accumulation of adenosine and its metabolites, none of these agents potentiated inhibitory responses to intramural nerve stimulation or to application of adenosine, adenosine triphosphate or phenylephrine. These results neither support nor dispute the suggestion that adenosine or a related nucleotide is the intramural inhibitory transmitter but do show that tissue accumulation in rabbit duodenum is not an important feature in the termination of the action of adenosine.

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Year:  1974        PMID： 4447864      PMCID： PMC1776734          DOI： 10.1111/j.1476-5381.1974.tb08598.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  9 in total

1.  Potentiation of the effects of exogenously applied ATP and purinergic nerve stimulation on the guinea-pig taenia coli by dipyridamole and hexobendine.

Authors:  D G Satchell; A Lynch; P M Bourke; G Burnstock
Journal:  Eur J Pharmacol       Date:  1972-09       Impact factor: 4.432

2.  Noradrenaline storage particles in splenic nerve.

Authors:  W P De Potter
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1971-06-17       Impact factor: 6.237

Review 3.  Purinergic nerves.

Authors:  G Burnstock
Journal:  Pharmacol Rev       Date:  1972-09       Impact factor: 25.468

Review 4.  The nervous release and the action of substances which affect intestinal muscle through neither adrenoreceptors nor cholinoreceptors.

Authors:  J B Furness; M Costa
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1973-03-15       Impact factor: 6.237

5.  Potentiation of adenosine and the adenine nucleotides by dipyridamole.

Authors:  A Stafford
Journal:  Br J Pharmacol Chemother       Date:  1966-11

6.  The accumulation of adenosine in rabbit intestinal muscle.

Authors:  M E Hulme; A H Weston
Journal:  Br J Pharmacol       Date:  1974-04       Impact factor: 8.739

7.  Nerve-mediated inhibition of mechanical activity in rabbit duodenum and the effects of desensitization to adenosine and several of its derivatives.

Authors:  A H Weston
Journal:  Br J Pharmacol       Date:  1973-06       Impact factor: 8.739

8.  Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non-adrenergic inhibitory nerves in the gut.

Authors:  G Burnstock; G Campbell; D Satchell; A Smythe
Journal:  Br J Pharmacol       Date:  1970-12       Impact factor: 8.739

9.  [3H]adenosine triphosphate: release during stimulation of enteric nerves.

Authors:  C Su; J A Bevan; G Burnstock
Journal:  Science       Date:  1971-07-23       Impact factor: 47.728
  9 in total
  3 in total

1.  Effects of some purine derivatives on the guinea-pig trachea and their interaction with drugs that block adenosine uptake.

Authors:  R A Coleman
Journal:  Br J Pharmacol       Date:  1976-05       Impact factor: 8.739

2.  Dissimilarity between the responses to adenosine triphosphate or its related compounds and non-adrenergic inhibitory nerve stimulation in the longitudinal smooth muscle of pig stomach.

Authors:  A Ohga; T Taneike
Journal:  Br J Pharmacol       Date:  1977-06       Impact factor: 8.739

3.  The accumulation of adenosine in rabbit intestinal muscle.

Authors:  M E Hulme; A H Weston
Journal:  Br J Pharmacol       Date:  1974-04       Impact factor: 8.739
  3 in total

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