Literature DB >> 4447863

The effect of bretylium on endogenous and newly-synthesized noradrenaline in the microsomal fraction of rat heart.

E T Abbs, C J Pycock.   

Abstract

Bretylium reduced the content of endogenous and newly-synthesized noradrenaline (NA) and also reduced the specific activity of NA in the microsomal fraction of rat heart. Bretylium also decreased the endogenous NA content of the microsomal subfraction which equilibrated in the 0.7 M sucrose region of a density gradient; it was without effect on the NA content of other subfractions.

Entities:  

Mesh：

Substances：

Year:  1974        PMID： 4447863      PMCID： PMC1776732          DOI： 10.1111/j.1476-5381.1974.tb08597.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  11 in total

1.  The contribution of small and large vesicles to noradrenaline release.

Authors:  M Fillenz; P R Howe
Journal:  J Physiol       Date:  1971-01       Impact factor: 5.182

Review 2.  Synaptic vesicles in sympathetic neurons.

Authors:  L B Geffen; B G Livett
Journal:  Physiol Rev       Date:  1971-01       Impact factor: 37.312

3.  Fine structure of noradrenaline storage vesicles in nerve terminals of the rat vas deferens.

Authors:  M Fillenz
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1971-06-17       Impact factor: 6.237

4.  The effects of bretylium on the subcellular distribution of noradrenaline and on adrenergic nerve function in rat heart.

Authors:  E T Abbs; C J Pycock
Journal:  Br J Pharmacol       Date:  1973-09       Impact factor: 8.739

5.  Selective release of newly synthesized norepinephrine from the cat spleen during sympathetic nerve stimulation.

Authors:  I J Kopin; G R Breese; K R Krauss; V K Weise
Journal:  J Pharmacol Exp Ther       Date:  1968-06       Impact factor: 4.030

6.  Light and heavy norepinephrine storage particles in the rat heart and in bovine splenic nerve.

Authors:  R H Roth; L Stjärne; F E Bloom; N J Giarman
Journal:  J Pharmacol Exp Ther       Date:  1968-08       Impact factor: 4.030

7.  The storage of endogenous noradrenaline in sympathetic nerve terminals.

Authors:  M A Bisby; M Fillenz
Journal:  J Physiol       Date:  1971-05       Impact factor: 5.182

8.  The validity of mitochondrial marker enzymes in rat heart.

Authors:  C J Pycock; S R Nahorski
Journal:  J Mol Cell Cardiol       Date:  1971-12       Impact factor: 5.000

9.  The release of catechol amines by choline 2,6-XYLYL ether, bretylium and guanethidine.

Authors:  E T Abbs
Journal:  Br J Pharmacol Chemother       Date:  1966-01

10.  Selective depletion of noradrenaline: a proposed mechanism of the adrenergic neurone-blocking action of bretylium.

Authors:  E T Abbs; M I Robertson
Journal:  Br J Pharmacol       Date:  1970-04       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.