Literature DB >> 444344

Effects of ageing on the pharmacokinetics of pancuronium.

K McLeod, C J Hull, M J Watson.   

Abstract

The effects of age on the pharmacokinetics of pancuronium were investigated. The distribution volume of pancuronium did not appear to be age-dependent, but elimination of the drug decreased with increasing age. The clinical implications of these findings are discussed.

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Year:  1979        PMID: 444344     DOI: 10.1093/bja/51.5.435

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  8 in total

Review 1.  Clinical pharmacokinetics of the newer neuromuscular blocking drugs.

Authors:  D P Atherton; J M Hunter
Journal:  Clin Pharmacokinet       Date:  1999-03       Impact factor: 6.447

Review 2.  Anaesthesia in the elderly. Special considerations.

Authors:  A G Jones; J M Hunter
Journal:  Drugs Aging       Date:  1996-11       Impact factor: 3.923

Review 3.  Neuromuscular transmission and its pharmacological blockade. Part 4: Use of relaxants in paediatric and elderly patients, in obstetrics, and in the intensive care unit.

Authors:  L H Booij
Journal:  Pharm World Sci       Date:  1997-02

Review 4.  Pharmacokinetics in intravenous anaesthetic practice.

Authors:  P Duvaldestin
Journal:  Clin Pharmacokinet       Date:  1981 Jan-Feb       Impact factor: 6.447

Review 5.  Clinical pharmacokinetics of the non-depolarising muscle relaxants.

Authors:  M I Ramzan; A A Somogyi; J S Walker; C A Shanks; E J Triggs
Journal:  Clin Pharmacokinet       Date:  1981 Jan-Feb       Impact factor: 6.447

Review 6.  Selecting neuromuscular-blocking drugs for elderly patients.

Authors:  Tristan M Cope; Jennifer M Hunter
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

7.  Pharmacokinetic and pharmacodynamic modelling with pancuronium.

Authors:  M A Evans; C A Shanks; K F Brown; E J Triggs
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

8.  Pharmacodynamic behaviour of rocuronium in the elderly.

Authors:  D R Bevan; P Fiset; P Balendran; J C Law-Min; A Ratcliffe; F Donati
Journal:  Can J Anaesth       Date:  1993-02       Impact factor: 5.063

  8 in total

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