Literature DB >> 444227

Effects of carbon tetrachloride on isolated rat hepatocytes. Inhibition of protein and lipoprotein secretion.

E Gravela, E Albano, M U Dianzani, G Poli, T F Slater.   

Abstract

The effects of carbon tetrachloride on protein and lipoprotein secretion, and on lipid peroxidation, have been investigated in isolated rat hepatocytes. It was found that although the free-radical scavenger promethazine completely suppressed the increased peroxidation produced by carbon tetrachloride, it had no effect on the inhibitory action of carbon tetrachloride on lipoprotein secretion. In consequence, the latter effect of carbon tetrachloride does not appear to be mediated through a peroxidative stage.

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Year:  1979        PMID： 444227      PMCID： PMC1186542          DOI： 10.1042/bj1780509

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  Critical role of lipid peroxidation in carbon tetrachloride-induced loss of aminopyrine demethylase, cytochrome P-450 and glucose 6-phosphatase.

Authors:  E A Glende; A M Hruszkewycz; R O Recknagel
Journal:  Biochem Pharmacol       Date:  1976-10-01       Impact factor: 5.858

2.  CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM.

Authors:  R G HAM
Journal:  Proc Natl Acad Sci U S A       Date:  1965-02       Impact factor: 11.205

3.  The extrusion of protein from the rabbit polymorphonuclear leucocyte treated with staphylococcal leucocidin.

Authors:  A M WOODIN
Journal:  Biochem J       Date:  1962-01       Impact factor: 3.857

4.  Albumin, fibrinogen and transferrin synthesis in isolated rat hepatocyte suspensions. A model for the study of plasma protein synthesis.

Authors:  K N Jeejeebhoy; J Ho; G R Greenberg; M J Phillips; A Bruce-Robertson; U Sodtke
Journal:  Biochem J       Date:  1975-01       Impact factor: 3.857

5.  Studies on the relatipnships between carbon tetrachloride-induced alterations of liver microsomal lipids and impairment of glucose-6-phosphatase activity.

Authors:  A Benedetti; A F Casini; M Ferrali; M Comporti
Journal:  Exp Mol Pathol       Date:  1977-12       Impact factor: 3.362

Review 6.  Carbon tetrachloride hepatotoxicity.

Authors:  R O Recknagel
Journal:  Pharmacol Rev       Date:  1967-06       Impact factor: 25.468

7.  Studies on fatty liver with isolated hepatocytes. I. The action of colchicine, phalloidin, cytochalasin B, and cyclohexamide on protein and triglyceride synthesis and secretion.

Authors:  E Gravela; G Poli; E Albano; M U Dianzani
Journal:  Exp Mol Pathol       Date:  1977-12       Impact factor: 3.362

8.  Effects of carbon tetrachloride on isolated rat liver cells: stimulation of lipid peroxidation and inhibitory action of free-radical scavengers [proceedings].

Authors:  G Poli; M P Chiono; T F Slater; M U Dianzani; E Gravela
Journal:  Biochem Soc Trans       Date:  1978       Impact factor: 5.407

9.  The effect of diet and vitamin E on liver injury due to carbon tetrachloride.

Authors:  A E McLean
Journal:  Br J Exp Pathol       Date:  1967-12
  9 in total
  7 in total

1.  Influence of lipid peroxidation on lipoprotein secretion by isolated hepatocytes.

Authors:  M U Dianzani; G Poli; E Gravela; E Chiarpotto; E Albano
Journal:  Lipids       Date:  1981-11       Impact factor: 1.880

2.  Hepatoprotective effects of Gentianella turkestanerum extracts on acute liver injury induced by carbon tetrachloride in mice.

Authors:  Jianghua Yang; Dandan Zhu; Bowei Ju; Xiangying Jiang; Junping Hu
Journal:  Am J Transl Res       Date:  2017-02-15       Impact factor: 4.060

3.  Effect of vitamin K on carbon tetrachloride-induced cellular damage in primary cultured rat hepatocytes.

Authors:  Y Itoh; A Terano
Journal:  Gastroenterol Jpn       Date:  1990-08

4.  Dependence of the carbon-tetrachloride--induced death of cultured hepatocytes on the extracellular calcium concentration.

Authors:  A F Casini; J L Farber
Journal:  Am J Pathol       Date:  1981-11       Impact factor: 4.307

5.  Course of ATP depletion in hydrazine hepatotoxicity.

Authors:  N E Preece; S Ghatineh; J A Timbrell
Journal:  Arch Toxicol       Date:  1990       Impact factor: 5.153

6.  Protective effect of ethyl acetate fraction of Rhododendron arboreum flowers against carbon tetrachloride-induced hepatotoxicity in experimental models.

Authors:  Neeraj Verma; Anil P Singh; G Amresh; P K Sahu; Ch V Rao
Journal:  Indian J Pharmacol       Date:  2011-05       Impact factor: 1.200

7.  Cytotoxicity and hepatoprotective attributes of methanolic extract of Rumex vesicarius L.

Authors:  Asha Tukappa N K; Ramesh L Londonkar; Hanumantappa B Nayaka; Sanjeev Kumar C B
Journal:  Biol Res       Date:  2015-03-25       Impact factor: 5.612
  7 in total

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