Literature DB >> 4441863

Pruritic effect of bile salts.

J Kirby, K W Heaton, J L Burton.   

Abstract

The pruritic effect of purified bile salts has been tested by applying them to blister bases. All the salts tested were pruritogens, but the dihydroxy salts (especially unconjugated chenodeoxycholate) were more effective than the trihydroxy salts. This may explain the poor correlation between total serum bile salt concentration and pruritus in obstructive jaundice.

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Year:  1974        PMID： 4441863      PMCID： PMC1612871          DOI： 10.1136/bmj.4.5946.693

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  14 in total

1.  Relief of the pruritus of jaundice with a bile-acid sequestering resin.

Authors:  J B CAREY; G WILLIAMS
Journal:  JAMA       Date:  1961-05-06       Impact factor: 56.272

2.  The serum trihydroxy-dihydroxy bile acid ratio in liver and biliary tract disease.

Authors:  J B CAREY
Journal:  J Clin Invest       Date:  1958-11       Impact factor: 14.808

3.  Serum-bile-acid levels in liver disease.

Authors:  E C OSBORN; I D WOOTTON; L da SILVA; S SHERLOCK
Journal:  Lancet       Date:  1959-12-12       Impact factor: 79.321

4.  The release of histamine by pethidine, atropine, quinine, and other drugs.

Authors:  M SCHACHTER
Journal:  Br J Pharmacol Chemother       Date:  1952-12

5.  Histamine metabolism in diseases of the liver.

Authors:  R G MITCHELL; H R BUTT; C F CODE
Journal:  J Clin Invest       Date:  1954-09       Impact factor: 14.808

6.  Primary biliary cirrhosis.

Authors:  E H AHRENS; M A PAYNE; H G KUNKEL; W J EISENMENGER; S H BLONDHEIM
Journal:  Medicine (Baltimore)       Date:  1950-12       Impact factor: 1.889

Review 7.  Pathophysiology of pruritus associated with elevated bile acid levels in serum.

Authors:  J H Herndon
Journal:  Arch Intern Med       Date:  1972-10

8.  Quantification of the binding tendencies of cholestyramine. II. Mechanism of interaction with bile salt and fatty acid salt anions.

Authors:  W H Johns; T R Bates
Journal:  J Pharm Sci       Date:  1970-03       Impact factor: 3.534

9.  Quantification of the binding tendencies of cholestyramine. I. Effect of structure and added electrolytes on the binding of unconjugated and conjugated bile-salt anions.

Authors:  W H Johns; T R Bates
Journal:  J Pharm Sci       Date:  1969-02       Impact factor: 3.534

10.  Serum bile acids in liver disease.

Authors:  G Neale; B Lewis; V Weaver; D Panveliwalla
Journal:  Gut       Date:  1971-02       Impact factor: 23.059
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  21 in total

1.  Reduction of sodium deoxycholic acid-induced scratching behaviour by bradykinin B2 receptor antagonists.

Authors:  I Hayashi; M Majima
Journal:  Br J Pharmacol       Date:  1999-01       Impact factor: 8.739

Review 2.  Extrahepatic manifestations of cholestatic liver diseases: pathogenesis and therapy.

Authors:  Thomas Pusl; Ulrich Beuers
Journal:  Clin Rev Allergy Immunol       Date:  2005-04       Impact factor: 8.667

Review 3.  Jaundice associated pruritis: a review of pathophysiology and treatment.

Authors:  Ramez Bassari; Jonathan B Koea
Journal:  World J Gastroenterol       Date:  2015-02-07       Impact factor: 5.742

Review 4.  Intrahepatic cholestasis of pregnancy.

Authors:  Victoria Geenes; Catherine Williamson
Journal:  World J Gastroenterol       Date:  2009-05-07       Impact factor: 5.742

Review 5.  Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis.

Authors:  Vasiliy Ivanovich Reshetnyak
Journal:  World J Gastroenterol       Date:  2015-07-07       Impact factor: 5.742

6.  The efficacy of histamine antagonists as antipruritics in experimentally induced pruritus.

Authors:  M G Davies; R Marks; R J Horton; F E Storari
Journal:  Arch Dermatol Res       Date:  1979-10       Impact factor: 3.017

7.  The TGR5 receptor mediates bile acid-induced itch and analgesia.

Authors:  Farzad Alemi; Edwin Kwon; Daniel P Poole; TinaMarie Lieu; Victoria Lyo; Fiore Cattaruzza; Ferda Cevikbas; Martin Steinhoff; Romina Nassini; Serena Materazzi; Raquel Guerrero-Alba; Eduardo Valdez-Morales; Graeme S Cottrell; Kristina Schoonjans; Pierangelo Geppetti; Stephen J Vanner; Nigel W Bunnett; Carlos U Corvera
Journal:  J Clin Invest       Date:  2013-03-25       Impact factor: 14.808

Review 8.  Clinical features and management of primary biliary cirrhosis.

Authors:  Andrea Crosignani; Pier-Maria Battezzati; Pietro Invernizzi; Carlo Selmi; Elena Prina; Mauro Podda
Journal:  World J Gastroenterol       Date:  2008-06-07       Impact factor: 5.742

9.  [Pruritus and bile acids. Determination of sulfalithoglycocholate and glycocholate in suction blister fluid and in serum (author's transl)].

Authors:  W Bräuninger; K Bork; B Morsches; P Benes; G W Korting
Journal:  Arch Dermatol Res       Date:  1981       Impact factor: 3.017

Review 10.  Pathogenesis and treatment of pruritus in cholestasis.

Authors:  Andreas E Kremer; Ulrich Beuers; Ronald P J Oude-Elferink; Thomas Pusl
Journal:  Drugs       Date:  2008       Impact factor: 9.546
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