Literature DB >> 4436326

Identification of alpha-ketoglutaramate in rat liver, kidney, and brain. Relationship to glutamine transaminase and omega-amidase activities.

T E Duffy, A J Cooper, A Meister.   

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Year:  1974        PMID: 4436326

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


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  11 in total

1.  Comparative enzymology of (2S,4R)4-fluoroglutamine and (2S,4R)4-fluoroglutamate.

Authors:  Arthur J L Cooper; Boris F Krasnikov; John T Pinto; Hank F Kung; Jianyong Li; Karl Ploessl
Journal:  Comp Biochem Physiol B Biochem Mol Biol       Date:  2012-05-19       Impact factor: 2.231

2.  Enzymatic analysis of α-ketoglutaramate--a biomarker for hyperammonemia.

Authors:  Lenka Halámková; Shay Mailloux; Jan Halámek; Arthur J L Cooper; Evgeny Katz
Journal:  Talanta       Date:  2012-08-24       Impact factor: 6.057

3.  Urinary 2-hydroxy-5-oxoproline, the lactam form of α-ketoglutaramate, is markedly increased in urea cycle disorders.

Authors:  Tomiko Kuhara; Yoshito Inoue; Morimasa Ohse; Boris F Krasnikov; Arthur J L Cooper
Journal:  Anal Bioanal Chem       Date:  2011-02-06       Impact factor: 4.142

4.  Structural insights into the catalytic active site and activity of human Nit2/ω-amidase: kinetic assay and molecular dynamics simulation.

Authors:  Chin-Hsiang Chien; Quan-Ze Gao; Arthur J L Cooper; Jyun-Hong Lyu; Sheh-Yi Sheu
Journal:  J Biol Chem       Date:  2012-06-06       Impact factor: 5.157

5.  Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination.

Authors:  Boris F Krasnikov; Chin-Hsiang Chien; Regina Nostramo; John T Pinto; Edward Nieves; Myrasol Callaway; Jin Sun; Kay Huebner; Arthur J L Cooper
Journal:  Biochimie       Date:  2009-07-10       Impact factor: 4.079

6.  Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase.

Authors:  Arthur J L Cooper; John T Pinto; Boris F Krasnikov; Zoya V Niatsetskaya; Qian Han; Jianyong Li; David Vauzour; Jeremy P E Spencer
Journal:  Arch Biochem Biophys       Date:  2008-02-29       Impact factor: 4.013

7.  Reactions catalyzed by purified L-glutamine: keto-scyllo-inositol aminotransferase, an enzyme required for biosynthesis of aminocyclitol antibiotics.

Authors:  L A Lucher; Y M Chen; J B Walker
Journal:  Antimicrob Agents Chemother       Date:  1989-04       Impact factor: 5.191

Review 8.  α-Ketoglutaramate: an overlooked metabolite of glutamine and a biomarker for hepatic encephalopathy and inborn errors of the urea cycle.

Authors:  Arthur J L Cooper; Tomiko Kuhara
Journal:  Metab Brain Dis       Date:  2013-11-14       Impact factor: 3.584

9.  In vivo activity of glutaminase in the brain of hyperammonaemic rats measured by 15N nuclear magnetic resonance.

Authors:  K Kanamori; B D Ross
Journal:  Biochem J       Date:  1995-01-01       Impact factor: 3.857

10.  Assay and purification of omega-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the alpha-keto acid analogues of glutamine and asparagine.

Authors:  Boris F Krasnikov; Regina Nostramo; John T Pinto; Arthur J L Cooper
Journal:  Anal Biochem       Date:  2009-05-21       Impact factor: 3.365

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