Literature DB >> 443497

The growing demand for midtrimester amniocentesis: a systems approach to forecasting the need for facilities.

H F Selle, D W Holmes, M L Ingbar.   

Abstract

A predicted shift in composition of the child-bearing population of the United States to higher maternal ages by year 2000 indicates that the number of chromosomally abnormal offspring of women age 35 and over will increase by 64% while the total number of women increases only 21%. We formulated a conceptual model of a health care system that predicts demand for amniocentesis from prospective patients in any particular region, the number of defective offspring detected, and the future cost of custodial care using any given level of detection effort. It was found that as capacity of clinic facilities and use by women age 35 and over in the area increased, the expenditure for amniocentesis combined with the cost of custodial care for undetected offspring decreased, assuming termination of affected pregnancies. Use of this model will enable health care managers to anticipate need for facilities, and also guide the formulation of social policy in the provision of new health services by enabling them to take into account the predictable effects of these services upon other public services.

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Year:  1979        PMID: 443497      PMCID: PMC1618986          DOI: 10.2105/ajph.69.6.574

Source DB:  PubMed          Journal:  Am J Public Health        ISSN: 0090-0036            Impact factor:   9.308


  14 in total

1.  Estimated rates of Down syndrome in live births by one year maternal age intervals for mothers aged 20-49 in a New York State study-implications of the risk figures for genetic counseling and cost-benefit analysis of prenatal diagnosis programs.

Authors:  E B Hook; G M Chambers
Journal:  Birth Defects Orig Artic Ser       Date:  1977

2.  Down syndrome in live births by single year maternal age interval in a Swedish study: comparison with results from a New York State study.

Authors:  E B Hook; A Lindsjö
Journal:  Am J Hum Genet       Date:  1978-01       Impact factor: 11.025

3.  Prenatal diagnosis of genetic disorders. An analysis of experience with 600 cases.

Authors:  A Milunsky; L Atkins
Journal:  JAMA       Date:  1974-10-14       Impact factor: 56.272

4.  Prenatal diagnosis of genetic disorders.

Authors:  G S Omenn
Journal:  Science       Date:  1978-05-26       Impact factor: 47.728

5.  Prenatal genetic diagnosis: current status.

Authors:  M T Mennuti
Journal:  N Engl J Med       Date:  1977-11-03       Impact factor: 91.245

Review 6.  Current concepts in genetics. Prenatal diagnosis of genetic disorders.

Authors:  A Milunsky
Journal:  N Engl J Med       Date:  1976-08-12       Impact factor: 91.245

7.  Letter: Prospective data on risk of Down syndrome in relation to maternal age.

Authors:  M A Ferguson-Smith
Journal:  Lancet       Date:  1976-07-31       Impact factor: 79.321

8.  Estimates of maternal age-specific risks of Down-syndrome birth in women aged 34-41.

Authors:  E B Hook
Journal:  Lancet       Date:  1976-07-03       Impact factor: 79.321

9.  Prenatal diagnosis of genetic diseases.

Authors:  C J Epstein; M S Golbus
Journal:  Am Sci       Date:  1977 Nov-Dec       Impact factor: 0.548

10.  Preventing the birth of infants with Down's syndrome: a cost-benefit analysis.

Authors:  S Hagard; F A Carter
Journal:  Br Med J       Date:  1976-03-27
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  2 in total

1.  Projection of Down's syndrome births in the United States 1979-2000, and the potential effects of prenatal diagnosis.

Authors:  C A Huether
Journal:  Am J Public Health       Date:  1983-10       Impact factor: 9.308

2.  Is amniocentesis a disease prevention measure?

Authors:  G E Crum
Journal:  Am J Public Health       Date:  1979-09       Impact factor: 9.308

  2 in total

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