Literature DB >> 443066

Fasting and prolonged exercise increase vasoactive intestinal polypeptide (VIP) in plasma.

H Galbo, J Hilsted, J Fahrenkrug, O B Schaffalitzky De Muckadell.   

Abstract

6 young men had venous blood drawn during 4 experiments. The concentration of VIP in plasma increased markedly (from 1.8 (0--4.5) to 22.3 (7.8--43.8) pmol.1(-1), mean and range) during 3 h of mild bicycle exercise but not at all during an equivalent period of rest or during short term submaximal and maximal exercise. During 59 h of fasting, VIP increased from 3.6 (0.6--6.6) to 10.2 (6.6--13.8) pmol.1(-1) (p less than 0.05). The concentration of glucose in plasma decreased significantly during the prolonged exercise as well as during fasting. The known metabolic actions of VIP and the demonstrated increases in its plasma concentration during negative energy balance indicate that VIP is "a polypeptide of substrate need".

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Year:  1979        PMID: 443066     DOI: 10.1111/j.1748-1716.1979.tb06353.x

Source DB:  PubMed          Journal:  Acta Physiol Scand        ISSN: 0001-6772


  6 in total

1.  Glycogenolytic effect of vasoactive intestinal peptide in the rat in vivo.

Authors:  V Sánchez; R Goberna; J R Calvo
Journal:  Experientia       Date:  1991-06-15

2.  The plasma concentrations of secretin and vasoactive intestinal polypeptide (VIP) after long-term, strenuous exercise.

Authors:  O Oktedalen; P K Opstad; O B Schaffalitzky de Muckadell
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1983

3.  Physiological changes and gastro-intestinal symptoms as a result of ultra-endurance running.

Authors:  N J Rehrer; F Brouns; E J Beckers; W O Frey; B Villiger; C J Riddoch; P P Menheere; W H Saris
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1992

4.  The actions of calcitonin gene related peptide and vasoactive intestinal peptide as vasodilators in man in vivo and in vitro.

Authors:  S M Thom; A D Hughes; P Goldberg; G Martin; M Schachter; P S Sever
Journal:  Br J Clin Pharmacol       Date:  1987-08       Impact factor: 4.335

5.  The gastro-entero-pancreatic hormone response to fasting in obesity.

Authors:  W J Andrews; R W Henry; K G Alberti; K D Buchanan
Journal:  Diabetologia       Date:  1981-11       Impact factor: 10.122

6.  Physical activity and natural anti-VIP antibodies: potential role in breast and prostate cancer therapy.

Authors:  Milena Veljkovic; Violeta Dopsaj; Milivoj Dopsaj; Donald R Branch; Nevena Veljkovic; Maria M Sakarellos-Daitsiotis; Veljko Veljkovic; Sanja Glisic; Alfonso Colombatti
Journal:  PLoS One       Date:  2011-11-30       Impact factor: 3.240

  6 in total

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