| Literature DB >> 443046 |
E C Moore, R J Laffin, T Tomasi, R J Pickering, J Radl, H J Meuwissen.
Abstract
The IgA system in a patient with SCID and ADA deficiency showed heterogeneity. Serum IgA and stool secretory IgA (SIgA) levels were normal, but with altered kappa/lambda and A1/A2 subclass ratios; IgA in saliva and urine was deficient. Amounts of secretory component were normal. Jejunal and rectal biopsies showed prominent lymphonodular hyperplasia, but no cells containing IgA. A normal serum IgA level therefore does not always predict an intact secretory IgA system.Entities:
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Year: 1979 PMID： 443046 DOI： 10.1111/j.1651-2227.1979.tb05038.x
Source DB: PubMed Journal: Acta Paediatr Scand ISSN： 0001-656X