Granuloma size in the liver of mice with Schistosoma haematobium infection and Schistosoma mansoni challenge.

Swiss albino mice have been infected with S. haematobium and challenged with S. mansoni. S. haematobium infection in the mouse runs a course more or less parallel to that of S. mansoni infection. Granuloma has reached a maximal size at 135 days post infection and has regressed thereafter. Suppression of S. mansoni granuloma was observed in mice previously infected with S. haematobium. This manifests the presence of cross immunization.