| Literature DB >> 442179 |
M M Levine, D R Nalin, J P Craig, D Hoover, E J Bergquist, D Waterman, H P Holley, R B Hornick, N P Pierce, J P Libonati.
Abstract
Purified cholera toxoid is antigenic when given enterally and orally. Purified toxoid fails to provide protection against experimental challenge. Clinical cholera confers formidable protection against homologous or heterologous rechallenge. Failure to culture vibrios from intestinal fluid or stool of re-challenge volunteers suggests that the predominant immune mechanism is antibacterial rather than antitoxic.Entities:
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Year: 1979 PMID： 442179 DOI： 10.1016/0035-9203(79)90119-6
Source DB: PubMed Journal: Trans R Soc Trop Med Hyg ISSN： 0035-9203 Impact factor: 2.184