Literature DB >> 4418160

Inhibition of mitochondrial pyruvate transport by phenylpyruvate and alpha-ketoisocaproate.

A P Halestrap, M D Brand, R M Denton.   

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Year:  1974        PMID： 4418160     DOI： 10.1016/0005-2736(74)90140-0

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


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  41 in total

1.  Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease.

Authors:  Cláudia Funchal; Patrícia Fernanda Schuck; André Quincozes Dos Santos; Maria Caroline Jacques-Silva; Carmem Gottfried; Regina Pessoa-Pureur; Moacir Wajner
Journal:  Cell Mol Neurobiol       Date:  2006-02       Impact factor: 5.046

2.  Effect of alpha-ketoisocaproate and leucine on the in vivo oxidation of glutamate and glutamine in the rat brain.

Authors:  H R Zielke; Y Huang; P J Baab; R M Collins; C L Zielke; J T Tildon
Journal:  Neurochem Res       Date:  1997-09       Impact factor: 3.996

3.  Transport of pyruvate nad lactate into human erythrocytes. Evidence for the involvement of the chloride carrier and a chloride-independent carrier.

Authors:  A P Halestrap
Journal:  Biochem J       Date:  1976-05-15       Impact factor: 3.857

4.  Effects of ketone bodies on amino acid metabolism in isolated rat diaphragm.

Authors:  G Palaiologos; P Felig
Journal:  Biochem J       Date:  1976-03-15       Impact factor: 3.857

5.  Effect of hyperphenylalaninaemia on lipid synthesis from ketone bodies by rat brain.

Authors:  M S Patel; O E Owen
Journal:  Biochem J       Date:  1976-02-15       Impact factor: 3.857

6.  Purification of aldehyde dehydrogenase from rat liver mitochondria by alpha-cyanocinnamate affinity chromatography.

Authors:  R C Poole; A P Halestrap
Journal:  Biochem J       Date:  1989-04-01       Impact factor: 3.857

7.  Pyruvate and ketone-body transport across the mitochondrial membrane. Exchange properties, pH-dependence and mechanism of the carrier.

Authors:  A P Halestrap
Journal:  Biochem J       Date:  1978-06-15       Impact factor: 3.857

Review 8.  Cytoskeleton as a potential target in the neuropathology of maple syrup urine disease: insight from animal studies.

Authors:  R Pessoa-Pureur; M Wajner
Journal:  J Inherit Metab Dis       Date:  2007-06-14       Impact factor: 4.982

9.  The specificity and metabolic implications of the inhibition of pyruvate transport in isolated mitochondria and intact tissue preparations by alpha-Cyano-4-hydroxycinnamate and related compounds.

Authors:  A P Halestrap; R M Denton
Journal:  Biochem J       Date:  1975-04       Impact factor: 3.857

10.  Lipogenesis in the brain of suckling rats. Studies on the mechansim of mitochondrial-cytosolic carbon transfer.

Authors:  T B Patel; J B Clark
Journal:  Biochem J       Date:  1980-04-15       Impact factor: 3.857
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