| Literature DB >> 440965 |
A S Gambaryan, I A Morozov, T V Venkstern, A A Bayev.
Abstract
Each of the individual tRNAs immobilized on aminohydroxybutyl-cellulose (ABC) through their oxidized 3'-terminal binds affinitively all methylases present in the enzyme extract irrespective of whether this tRNA will be involved in the following step of methylation or not. These data allow to suggest that (a) the formation of a methylase-tRNA complex and the catalytic act of methylation are indeed autonomous processes and (b) the first step of interaction between tRNAs and tRNA methylases is rather unspecific and consists in the recognition of the whole class of tRNA molecules.Entities:
Mesh：
Substances：
Year: 1979 PMID： 440965 PMCID： PMC327748 DOI： 10.1093/nar/6.3.1001
Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971