| Literature DB >> 4407283 |
E Ruoslahti, M Salaspuro, H Pihko, L Andersson, M Seppälä.
Abstract
Raised serum alpha-fetoprotein levels measured by radioimmunoassay were found in 19 out of 24 (79%) patients with primary liver cancer and in 32 out of 311 (10%) patients with other liver diseases. The rise was transient in cases of hepatitis and a transient rise was also seen after alcohol intake ceased in two patients with cirrhosis. alpha-Fetoprotein levels exceeding 500 ng/ml were 30-50 times more common in primary liver cancer than in other liver diseases. A rise in level seems to reflect the extent of liver regeneration in liver diseases other than primary cancer.Entities:
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Year: 1974 PMID: 4407283 PMCID: PMC1610895 DOI: 10.1136/bmj.2.5918.527
Source DB: PubMed Journal: Br Med J ISSN: 0007-1447