Literature DB >> 4402818

Effects of gamma-hydroxybutyrate on chick behaviour, electrocortical activity and crossed extensor reflexes.

G Osuide.   

Abstract

1. Convulsant and anticonvulsant effects of gamma-hydroxybutyrate (GHB) have been studied in chicks.2. When administered alone, GHB produced weak myoclonic seizures accompanied by electrocortical synchrony and spikes.3. GHB was found to protect chicks against leptazol- and picrotoxin-induced seizures. A slight potentiation of strychnine-induced seizures was evident.

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Year:  1972        PMID： 4402818      PMCID： PMC1665996          DOI： 10.1111/j.1476-5381.1972.tb07299.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  19 in total

1.  EFFECTS OF TYRAMINE ON A SPINAL REFLEX IN THE ANAESTHETISED CHICK.

Authors:  W C BOWMAN; B A CALLINGHAM; G OSUIDE
Journal:  J Pharm Pharmacol       Date:  1964-08       Impact factor: 3.765

2.  CORRELATION OF BLOOD LEVELS OF 4-HYDROXYBUTYRATE WITH STATE OF CONSCIOUSNESS.

Authors:  M HELRICH; T C MCASLAN; S SKOLNIK; S P BESSMAN
Journal:  Anesthesiology       Date:  1964 Nov-Dec       Impact factor: 7.892

3.  PREPARATION AND IMPLANTATION OF BRAIN ELECTRODES IN THE YOUNG CHICK.

Authors:  C E SPOONER
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1965-03

4.  GAMMA-HYDROXYBUTYRATE IN MAMMALIAN BRAIN. REVERSIBLE OXIDATION BY LACTIC DEHYDROGENASE.

Authors:  W N FISHBEIN; S P BESSMAN
Journal:  J Biol Chem       Date:  1964-01       Impact factor: 5.157

5.  PRELIMINARY REPORT ON THE METABOLISM OF GAMMA-BUTYROLACTONE AND GAMMA-HYDROXYBUTYRIC ACID.

Authors:  R H ROTH; N J GIARMAN
Journal:  Biochem Pharmacol       Date:  1965-02       Impact factor: 5.858

6.  [Radioprotective action of sodium gamma-hydroxybutyrate (preliminary notes)].

Authors:  M DANA; C BARON; H LABORIT
Journal:  Agressologie       Date:  1962 May-Jun

7.  A neurophysiological comparison of alpha-chloralose with gamma-hydroxybutyrate in cats.

Authors:  W D Winters; C E Spooner
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1966-01

8.  Intra-arterial blood pressure recording in the unrestrained chick during wakefulness and sleep.

Authors:  C E Spooner; W D Winters
Journal:  Arch Int Pharmacodyn Ther       Date:  1966-05

9.  EEG and behavioral comparison of the effects of gamma-hydroxybutyrate, gamma-butyrolactone and short chain fatty acids in the rat.

Authors:  R J Marcus; W D Winters; K Mori; C E Spooner
Journal:  Int J Neuropharmacol       Date:  1967-05

10.  PARADOXICAL PHASE OF SLEEP: ITS ARTIFICIAL INDUCTION IN THE CAT BY SODIUM BUTYRATE.

Authors:  M MATSUZAKI; H TAKAGI; T TOKIZANE
Journal:  Science       Date:  1964-12-04       Impact factor: 47.728
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