Literature DB >> 44015

[Controlled therapeutic study of spontaneous bucco-linguo-facial dyskinesias (author's transl)].

P J Delwaide, M Desseilles.   

Abstract

A triple blind study has been conducted according to an original methodology to compare the effects of thioproperazine and tiapride on the spontaneous bucco-linguo-facial dyskinesias in the elderly. Side effects have been balanced to obtain a quantitative evaluation. Thioproperazine (3 x 3 mg/day) and tiapride (3 x 100 mg/day) reduce both significantly the number of dyskinesias, the former being more active than the latter. On the other hand, side effects of thioproprerazine are significantly higher than those of tiapride which are themselves not different from those induced by the placebo. Taking into account these results and the fact that dyskinesias represent a benign condition, the tiapride appears to be the first choice drug.

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Year:  1979        PMID: 44015

Source DB:  PubMed          Journal:  Sem Hop


  4 in total

Review 1.  Antipsychotic medication for elderly people with schizophrenia.

Authors:  R G Marriott; W Neil; S Waddingham
Journal:  Cochrane Database Syst Rev       Date:  2006-01-25

2.  Neuroleptic-induced acute dyskinesias in rhesus monkeys.

Authors:  R D Porsolt; M Jalfre
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

Review 3.  Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia.

Authors:  Hanna Bergman; John Rathbone; Vivek Agarwal; Karla Soares-Weiser
Journal:  Cochrane Database Syst Rev       Date:  2018-02-06

Review 4.  Non-antipsychotic catecholaminergic drugs for antipsychotic-induced tardive dyskinesia.

Authors:  Hany G El-Sayeh; John Rathbone; Karla Soares-Weiser; Hanna Bergman
Journal:  Cochrane Database Syst Rev       Date:  2018-01-18
  4 in total

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