Literature DB >> 4398761

Actinomycin-D enhancement of glutamine synthetase activity in chick embryo retinas cultured in the presence of cortisol.

L Reif-Lehrer.   

Abstract

Cortisol can prematurely induce glutamine synthetase activity in the chick embryo retina. Under appropriate conditions, this effect can be enhanced by addition of low levels of actinomycin D; this enhancement is reversibly inhibited by cycloheximide. The magnitude of the effect is a function of time of exposure to hormone as well as antibiotic and is also a function of the age of the embryo; within the limits of the present study it did not appear to be a function of actinomycin-D concentration. The data are discussed in terms of current ideas of possible control mechanisms in animal cells.

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Year:  1971        PMID: 4398761      PMCID: PMC2108240          DOI: 10.1083/jcb.51.1.303

Source DB:  PubMed          Journal:  J Cell Biol        ISSN: 0021-9525            Impact factor:   10.539


  15 in total

1.  Enzyme induction in embryonic retina: the role of transcription and translation.

Authors:  A A Moscona; M H Moscona; N Saenz
Journal:  Proc Natl Acad Sci U S A       Date:  1968-09       Impact factor: 11.205

2.  Control of specific gene expression in higher organisms. Expression of mammalian genes may be controlled by repressors acting on the translation of messenger RNA.

Authors:  G M Tomkins; T D Gelehrter; D Granner; D Martin; H H Samuels; E B Thompson
Journal:  Science       Date:  1969-12-19       Impact factor: 47.728

3.  Precocious induction of retinal glutamine synthetase by hydrocortisone in the embryo and in culture. Age-dependent differences in tissue response.

Authors:  R Piddington; A A Moscona
Journal:  Biochim Biophys Acta       Date:  1967-07-25

4.  Effect of inhibitors of nucleic acid synthesis on steroid-mediated induction of tyrosine aminotransferase in hepatoma cell cultures.

Authors:  B Peterkofsky; G M Tomkins
Journal:  J Mol Biol       Date:  1967-11-28       Impact factor: 5.469

5.  "Superinduction" of tyrosine transaminase in hepatoma cell cultures: differential inhibition of synthesis and turnover by actionomycin D.

Authors:  J R Reel; F T Kenney
Journal:  Proc Natl Acad Sci U S A       Date:  1968-09       Impact factor: 11.205

6.  A sensitive assay for glutamyltransferase.

Authors:  J Thorndike; L Reif-Lehrer
Journal:  Enzyme       Date:  1971

7.  Induction of glutamine synthetase in chick embryo retina: effects of serum and of steroid structure.

Authors:  L Reif-Lehrer
Journal:  Biochim Biophys Acta       Date:  1968-12-23

8.  Stimulation by hydrocortisone of premature changes in the developmental pattern of glutamine synthetase in embryonic retina.

Authors:  A A Moscona; R Piddington
Journal:  Biochim Biophys Acta       Date:  1966-06-29

9.  Control of specific gene expression examined in synchronized mammalian cells.

Authors:  D W Martin; G M Tomkins; M A Bresler
Journal:  Proc Natl Acad Sci U S A       Date:  1969-07       Impact factor: 11.205

10.  Glutamine synthetase in the normal and dystorphic mouse retina.

Authors:  M M Lavail; L Reif-Lehrer
Journal:  J Cell Biol       Date:  1971-10       Impact factor: 10.539

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  6 in total

1.  Effect of dissociative methods on cortisol binding and glutamyltransferase inducibility in chick embryo retina.

Authors:  J B Piperberg; L Reif-Lehrer
Journal:  Cell Biophys       Date:  1981-06

2.  Glutamine, insulin and glucocorticoids regulate glutamine synthetase expression in C2C12 myotubes, Hep G2 hepatoma cells and 3T3 L1 adipocytes.

Authors:  Yanxin Wang; Malcolm Watford
Journal:  Biochim Biophys Acta       Date:  2006-11-23

3.  Glutamine synthetase in cultured whole retinas from the embryonic chick. Role of protein and RNA syntheses in 4 degrees C storage enhancement.

Authors:  J B Piperberg; L Reif-Lehrer
Journal:  Cell Biophys       Date:  1984-06

4.  Effect of washout of inducing steroid on gamma-glutamyl transferase activity in the cultured chick embryo retina.

Authors:  L Reif-Lehrer
Journal:  J Cell Biol       Date:  1974-10       Impact factor: 10.539

5.  Interrelationship between differentiation and malignancy-associated properties in glioma.

Authors:  M C Frame; R I Freshney; P F Vaughan; D I Graham; R Shaw
Journal:  Br J Cancer       Date:  1984-03       Impact factor: 7.640

6.  Glutamine synthetase localization in cortisol-induced chick embryo retinas.

Authors:  M D Norenberg; K Dutt; L Reif-Lehrer
Journal:  J Cell Biol       Date:  1980-03       Impact factor: 10.539

  6 in total

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