| Literature DB >> 4397171 |
Abstract
Fifteen of twenty-one perfused human umbilical artery preparations constricted in response to tyramine. These responses were unaffected by atropine, mepyramine or bromolysergic acid diethylamide but were blocked by phentolamine or dihydroergotamine. Cocaine augmented the constriction responses to tyramine or noradrenaline but not those to adrenaline, acetylcholine or 5-hydroxytryptamine. Infusion of noradrenaline restored the responses of preparations which had become tachyphylactic to tyramine.Entities:
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Year: 1971 PMID： 4397171 PMCID： PMC1666998 DOI： 10.1111/j.1476-5381.1971.tb07096.x
Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739