Literature DB >> 4393821

Reduced nicotinamide-adenine dinucleotide phosphate oxidase: activity enhanced by ethanol consumption.

C S Lieber, L M DeCarli.   

Abstract

Prolonged consumption of ethanol enhances the activities of the hepatic microsomal ethanol oxidizing system and of reduced nicotinamide-adenine dinucleotide phosphate oxidase, but not of catalase. The oxidase-catalase system is not part of the microsomal ethanol oxidizing system since catalase inhibitors dissociate ethanol oxidation by the two pathways. Enhanced reduced nicotinamide-adenine dinucleotide phosphate oxidase activity may contribute to liver injury, possibly by favoring lipoperoxidation.

Entities:  

Mesh：

Substances：

Year:  1970        PMID： 4393821     DOI： 10.1126/science.170.3953.78

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  Lipid peroxidation and antioxidant systems in rat brain: effect of chronic alcohol consumption.

Authors:  F Omodeo-Sale; D Gramigna; R Campaniello
Journal:  Neurochem Res       Date:  1997-05       Impact factor: 3.996

2.  Metabolic alterations produced in the liver by chronic ethanol administration. Increased oxidative capacity.

Authors:  L Videla; J Bernstein; Y Israel
Journal:  Biochem J       Date:  1973-06       Impact factor: 3.857

3.  Effects of ethanol upon lipid metabolism.

Authors:  C S Lieber
Journal:  Lipids       Date:  1974-02       Impact factor: 1.880

4.  Studies on in vitro peroxidation of liver lipids in ethanol-treated rats.

Authors:  M Comporti; A Benedetti; E Chieli
Journal:  Lipids       Date:  1973-09       Impact factor: 1.880

5.  Lipid peroxidation in chronic ethanol treated rats: in vitro uncoupling of peroxidation from reduced nicotine adenosine dinucleotide phosphate oxidation.

Authors:  M Koes; T Ward; S Pennington
Journal:  Lipids       Date:  1974-11       Impact factor: 1.880

6.  Ethanol oxidizing enzyme activites in liver disease.

Authors:  J Dow; N Krasner; A Goldberg
Journal:  Br J Clin Pharmacol       Date:  1976-06       Impact factor: 4.335

7.  Liver alcohol oxidizing systems and gluconeogenic enzyme activities after long term ethanol application in cold exposed guinea pigs.

Authors:  V Kinnula; P Huttunen
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1984

8.  In vitro and in vivo effects of ethanol on the formation of endoperoxide metabolites in rat platelets.

Authors:  D H Hwang; P LeBlanc; P Chanmugan
Journal:  Lipids       Date:  1981-08       Impact factor: 1.880

9.  DNA strand cleavage as a sensitive assay for the production of hydroxyl radicals by microsomes: role of cytochrome P4502E1 in the increased activity after ethanol treatment.

Authors:  E Kukielka; A I Cederbaum
Journal:  Biochem J       Date:  1994-09-15       Impact factor: 3.857

Review 10.  Drug interactions with alcohol.

Authors:  M Linnoila; M J Mattila; B S Kitchell
Journal:  Drugs       Date:  1979-10       Impact factor: 9.546
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.