Literature DB >> 438986

Synthesis of 3-hydroxy-3-phenacyloxindole analogs.

F D Popp, B E Donigan.   

Abstract

Substituted isatins and substituted acetophenones were condensed to give analogs of 3-hydroxy-3-phenacyloxindole. These alcohols were dehydrated, and the alkene was reduced. None of the products had the level of anticonvulsant activity exhibited by the parent compound.

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Year:  1979        PMID: 438986     DOI: 10.1002/jps.2600680437

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  2 in total

1.  Preparation and antioxidant/pro-oxidant activities of 3-monosubstituted 5-hydroxyoxindole derivatives.

Authors:  Daisuke Yasuda; Kyoko Takahashi; Tomoyuki Ohe; Shigeo Nakamura; Tadahiko Mashino
Journal:  J Clin Biochem Nutr       Date:  2016-08-24       Impact factor: 3.114

2.  Synthesis and in vitro antioxidant activity of new 3-substituted-2-oxindole derivatives.

Authors:  A K Gupta; S Kalpana; J K Malik
Journal:  Indian J Pharm Sci       Date:  2012-09       Impact factor: 0.975

  2 in total

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