Literature DB >> 438967

Improved delivery of methoxsalen.

J Kreuter, T Higuchi.   

Abstract

Significant improvement in the effective bioavailability of methoxsalen was achieved when it was administered to rats and dogs in a solution as compared to a suspension. Much earlier and higher peak levels were observed for the solution in both animals. The possible impact of these observations on current use of this agent for psoriasis treatment is discussed.

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Year:  1979        PMID： 438967     DOI： 10.1002/jps.2600680415

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  3 in total

1.  Difference in bioavailability between two brands of 8-methoxypsoralen and its impact on the clinical response in psoriatic patients.

Authors:  M J Herfst; F A De Wolff
Journal:  Br J Clin Pharmacol       Date:  1982-04       Impact factor: 4.335

2.  Intraindividual variations of 8-methoxypsoralen plasma levels.

Authors:  M Schäfer-Korting; H C Korting
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017

3.  Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method.

Authors:  H C Korting; M Schäfer-Korting; E Roser-Maass; E Mutschler
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017
  3 in total

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