Literature DB >> 438962

Predictability of warfarin dose requirements: theoretical considerations.

W T Sawyer.   

Abstract

The theoretical basis of the predictability of warfarin maintenance dose requirements was evaluated using computer-generated hypothetical patient responses to a 10-mg/day "loading" dose regimen. Correlations between these responses and projected maintenance dose requirements were evaluated statistically, and a significant relationship was identified.

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Year:  1979        PMID: 438962     DOI: 10.1002/jps.2600680410

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  3 in total

1.  A simple technique for predicting maintenance dosage of warfarin--is it better than empirical dosing?

Authors:  L Ovesen; S Lyduch; P Ott
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

Review 2.  Pharmacokinetic optimisation of the treatment of deep vein thrombosis.

Authors:  A Iorio; G Agnelli
Journal:  Clin Pharmacokinet       Date:  1997-02       Impact factor: 6.447

Review 3.  Clinical pharmacokinetics and pharmacodynamics of warfarin. Understanding the dose-effect relationship.

Authors:  N H Holford
Journal:  Clin Pharmacokinet       Date:  1986 Nov-Dec       Impact factor: 6.447

  3 in total

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