Literature DB >> 4386372

5-Hydroxytryptamine metabolism in rat brain and liver homogenates.

A Feldstein, O Williamson.   

Abstract

1. The metabolism of 5-hydroxyindoleacetaldehyde derived from 5-hydroxytryptamine incubated with tissue homogenates was studied as an indicator of aldehyde dehydrogenase and alcohol dehydrogenase activities.2. In liver and brain from rats, there were indications of the presence of one or more aldehyde dehydrogenases which were stimulated by NAD(+) to a greater extent than by NADP(+).3. In liver from rats, there were indications of the presence of one or more alcohol dehydrogenases, which were stimulated by NADH to a greater extent than by NADPH.4. In brain from rats, there were indications of the presence of one or more alcohol dehydrogenases which were stimulated by NADPH to a greater extent than by NADH.

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Year:  1968        PMID: 4386372      PMCID: PMC1703398          DOI: 10.1111/j.1476-5381.1968.tb07948.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  10 in total

1.  ENZYMATIC CONVERSION OF SEROTONIN TO 5-HYDROXYTRYPTOPHOL.

Authors:  A FELDSTEIN; K K WONG
Journal:  Life Sci (1962)       Date:  1965-01

2.  5-Hydroxytryptophol: a metabolite of 5-hydroxytryptamine in rats.

Authors:  S KVEDER; S ISKRIC; D KEGLEVIC
Journal:  Biochem J       Date:  1962-12       Impact factor: 3.857

3.  Soluble monoamine oxidase; its properties and actions on serotonin.

Authors:  H WEISSBACH; B G REDFIELD; S UDENFRIEND
Journal:  J Biol Chem       Date:  1957-12       Impact factor: 5.157

4.  Enzymatic dephosphorylation of triphosphopyridine nucleotide.

Authors:  D R SANADI
Journal:  Arch Biochem Biophys       Date:  1952-02       Impact factor: 4.013

5.  The separation of DPN-linked and TPN-linked isocitrate dehydrogenase activities of mammalian liver.

Authors:  G W Plaut; T Aogaichi
Journal:  Biochem Biophys Res Commun       Date:  1967-08-23       Impact factor: 3.575

6.  Tissue and subcellular distribution of mammalian aldehyde-oxydizing capacity.

Authors:  R A Deitrich
Journal:  Biochem Pharmacol       Date:  1966-12       Impact factor: 5.858

7.  Analysis of 5-HTP-C-14 and its metabolites.

Authors:  A Feldstein; K K Wong
Journal:  Anal Biochem       Date:  1965-06       Impact factor: 3.365

8.  Brain aldehyde dehydrogenase. Localization, purification, and properties.

Authors:  V G Erwin; R A Deitrich
Journal:  J Biol Chem       Date:  1966-08-10       Impact factor: 5.157

9.  Serotonin metabolism in pineal homogenates.

Authors:  A Feldstein; O Williamson
Journal:  Adv Pharmacol       Date:  1968

10.  THE ACTIVITY OF LIVER ALCOHOL DEHYDROGENASE WITH NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE AS COENZYME.

Authors:  K DALZIEL; F M DICKINSON
Journal:  Biochem J       Date:  1965-05       Impact factor: 3.857

  10 in total
  4 in total

1.  The role of serotonin and possible interaction of serotonin-related genes with alcohol dehydrogenase and aldehyde dehydrogenase genes in alcohol dependence-a review.

Authors:  Charles Lung-Cheng Huang
Journal:  Am J Transl Res       Date:  2010-03-25       Impact factor: 4.060

Review 2.  Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence.

Authors:  Marco Bortolato; Jean C Shih
Journal:  Int Rev Neurobiol       Date:  2011       Impact factor: 3.230

3.  Simulation of biogenic amine metabolism in the brain.

Authors:  A J Turner; J A Illingworth; K F Tipton
Journal:  Biochem J       Date:  1974-11       Impact factor: 3.857

Review 4.  From aggression to autism: new perspectives on the behavioral sequelae of monoamine oxidase deficiency.

Authors:  Marco Bortolato; Gabriele Floris; Jean C Shih
Journal:  J Neural Transm (Vienna)       Date:  2018-05-10       Impact factor: 3.575

  4 in total

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