Literature DB >> 438355

The respiratory effects of dezocine and pentazocine in man.

H P Wuest, J W Bellville.   

Abstract

The respiratory effects of dezocine and pentazocine were studied in five volunteers. Based on their effects over a 3-hour period, it was found that dezocine was 8.6 times as potent as pentazocine in terms of their respiratory depressant effects. The clinical significance of these findings remains to be determined.

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Year:  1979        PMID: 438355     DOI: 10.1002/j.1552-4604.1979.tb01653.x

Source DB:  PubMed          Journal:  J Clin Pharmacol        ISSN: 0091-2700            Impact factor:   3.126


  4 in total

1.  Pharmacokinetics of dezocine, a new analgesic: effect of dose and route of administration.

Authors:  A Locniskar; D J Greenblatt; M A Zinny
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953

Review 2.  Dezocine. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.

Authors:  J J O'Brien; P Benfield
Journal:  Drugs       Date:  1989-08       Impact factor: 9.546

Review 3.  Dezocine as a potent analgesic: overview of its pharmacological characterization.

Authors:  Rong-Rong Ye; Shuang Jiang; Xu Xu; Yan Lu; Yu-Jun Wang; Jing-Gen Liu
Journal:  Acta Pharmacol Sin       Date:  2021-11-04       Impact factor: 7.169

4.  Double-blind placebo-controlled comparison of dezocine and morphine for post-operative pain relief.

Authors:  S K Pandit; S P Kothary; U A Pandit; N R Kunz
Journal:  Can Anaesth Soc J       Date:  1985-11
  4 in total

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