| Literature DB >> 438232 |
C G Pitt, A R Jeffcoat, R A Zweidinger, A Schindler.
Abstract
The maximum steady state flux, diffusion coefficients, and solubilities of five contraceptive steroids in homopolymers and copolymers of epsilon-caprolactone and DL-lactic acid were determined. The permeabilities of polymers of epsilon-caprolactone were comparable to silicone rubber and, by inference, are suitable for the construction of drug delivery devices. Poly(DL-lactic acid) was 10(4) times less permeable, although its permeability was significantly enhanced by additives.Entities:
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Year: 1979 PMID： 438232 DOI： 10.1002/jbm.820130313
Source DB: PubMed Journal: J Biomed Mater Res ISSN： 0021-9304