Literature DB >> 4382032

The rise in clotting factor 8 induced in man by adrenaline: effect of alpha- and beta-blockers.

G I Ingram, R V Jones.   

Abstract

1. Human subjects received intravenous infusions of adrenaline preceded by saline, phentolamine (an alpha-blocker) or either pronethalol or propranalol (beta-blockers), in different experiments.2. Clinical measurements of blood pressure and pulse rate confirmed that alpha- or beta-blockade had been achieved.3. The rise in clotting factor VIII induced by adrenaline was blocked by pronethalol and propranalol but not by phentolamine. This indicated that the effect of adrenaline on factor VIII was mediated by beta-receptors.

Entities:  

Mesh：

Substances：

Year:  1966        PMID： 4382032      PMCID： PMC1395935          DOI： 10.1113/jphysiol.1966.sp008102

Source DB:  PubMed          Journal:  J Physiol        ISSN： 0022-3751            Impact factor:   5.182


  14 in total

1.  Effect of physical exercise on blood clotting and fibrinolysis.

Authors:  S G IATRIDIS; J H FERGUSON
Journal:  J Appl Physiol       Date:  1963-03       Impact factor: 3.531

2.  Pharmacology of a new adrenergic beta-receptor-blocking compound (Nethalide).

Authors:  J W BLACK; J S STEPHENSON
Journal:  Lancet       Date:  1962-08-18       Impact factor: 79.321

3.  Clinical pharmacology of a beta-adrenergic-blocking agent (Nethalide).

Authors:  A C DORNHORST; B F ROBINSON
Journal:  Lancet       Date:  1962-08-18       Impact factor: 79.321

4.  Increase in antihaemophilic globulin activity following infusion of adrenaline.

Authors:  G I INGRAM
Journal:  J Physiol       Date:  1961-04       Impact factor: 5.182

5.  Effect of exercise on the level of antihaemophilic globulin in human blood.

Authors:  C R RIZZA
Journal:  J Physiol       Date:  1961-04       Impact factor: 5.182

6.  Comparison in man of adrenergic blockade produced by Dibenzyline, Ilidar, Priscoline, and Regitine.

Authors:  H D GREEN
Journal:  Circulation       Date:  1957-01       Impact factor: 29.690

7.  Effect of antihemophilic factor on one-stage clotting tests; a presumptive test for hemophilia and a simple one-stage antihemophilic factor assy procedure.

Authors:  R D LANGDELL; R H WAGNER; K M BRINKHOUS
Journal:  J Lab Clin Med       Date:  1953-04

8.  An evaluation of the ability of priscoline, regitine, and roniacol to overcome vasospasm in normal man; estimation of the probable clinical efficacy of these drugs in vasospastic peripheral vascular disease.

Authors:  H D GREEN; W K GOBEL; M J MOORE; T C PRINCE
Journal:  Circulation       Date:  1952-10       Impact factor: 29.690

9.  Effects of regitine (C-7337) upon the blood flow responses to epinephrine in the innervated hind limb of the dog.

Authors:  G ROBERTS; A W RICHARDSON; H D GREEN
Journal:  J Pharmacol Exp Ther       Date:  1952-08       Impact factor: 4.030

10.  The effect of adrenaline infusions on blood coagulation in normal and haemophilia B dogs.

Authors:  A H Ozge; H C Rowsell; H G Downie; J F Mustard
Journal:  Thromb Diath Haemorrh       Date:  1966-05-15
View more
  7 in total

Review 1.  Hypertension: which beta-blocker?

Authors:  H J Waal-Manning
Journal:  Drugs       Date:  1976-12       Impact factor: 9.546

2.  Problems with Beta Adrenergic Blocking Drugs and other Antihypertensive Drugs.

Authors:  B N Prichard
Journal:  Proc R Soc Med       Date:  1977

3.  Elevated factor VIII increases the risk of cerebral venous thrombosis: a case-control study.

Authors:  Loes Vecht; Susanna M Zuurbier; Joost C M Meijers; Jonathan M Coutinho
Journal:  J Neurol       Date:  2018-05-08       Impact factor: 4.849

Review 4.  The second Lilly Prize Lecture, University of Newcastle, July 1977. beta-Adrenergic receptor blockade in hypertension, past, present and future.

Authors:  B N Prichard
Journal:  Br J Clin Pharmacol       Date:  1978-05       Impact factor: 4.335

Review 5.  Current studies in surgical shock.

Authors:  M Irving
Journal:  Proc R Soc Med       Date:  1972-12

6.  Effects of triiodothyronine-induced hypermetabolism on factor 8 and fibrinogen in man.

Authors:  J C Hoak; W R Wilson; E D Warner; E O Theilen; G L Fry; F L Benoit
Journal:  J Clin Invest       Date:  1969-04       Impact factor: 14.808

7.  Impact of Adrenal Function on Hemostasis/Endothelial Function in Patients Undergoing Surgery.

Authors:  Stefan Fischli; Viktor von Wyl; Walter Wuillemin; Roland von Känel; Philipp Schütz; Mirjam Christ-Crain; Fabian Studer; Lukas Brander; Guido Schüpfer; Jürg Metzger; Christoph Henzen
Journal:  J Endocr Soc       Date:  2021-03-23
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.