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Literature DB >> 438113

Histidinemia and infantile autism.

Abstract

A 10-year-old boy first showed features of infantile autism at age 24 months. Histidinemia was also diagnosed, with histidine blood levels seven times higher than the upper normal values. If the coexistence of autism and histidinemia was not coincidental, histidinemia may have constituted a necessary but not sufficient factor leading to the clinical condition of autism. Other members of the patient's family had high blood levels of histidine, but did not show symptoms that have been related to histidinemia.

Entities: Chemical Disease Species

Mesh：

Substances：
Histidine

Year: 1979 PMID： 438113 DOI： 10.1007/bf01531292

Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257

4 in total

1. Biochemical studies of children with the syndromes of autism, childhood schizophrenia and related developmental disabilities: a review.

Authors: E R Ritvo
Journal: J Child Psychol Psychiatry Date: 1977-09 Impact factor: 8.982

2. Routine newborn screening for histidinemia. Clinical and biochemical results.

Authors: H L Levy; V E Shih; P M Madigan
Journal: N Engl J Med Date: 1974-12-05 Impact factor: 91.245

3. Malabsorption and cerebral dysfunction: a multivariate and comparative study of autistic children.

Authors: M S Goodwin; M A Cowen; T C Goodwin
Journal: J Autism Child Schizophr Date: 1971 Jan-Mar

Review 4. Causes of infantile autism: some considerations from recent research.

Authors: M Rutter; L Bartak
Journal: J Autism Child Schizophr Date: 1971 Jan-Mar

4 in total

1. Receptor inhibition by immunoglobulins: specific inhibition by autistic children, their relatives, and control subjects.

Authors: E H Cook; B D Perry; G Dawson; M S Wainwright; B L Leventhal
Journal: J Autism Dev Disord Date: 1993-03

Histidinemia and infantile autism.

1. Biochemical studies of children with the syndromes of autism, childhood schizophrenia and related developmental disabilities: a review.

2. Routine newborn screening for histidinemia. Clinical and biochemical results.

3. Malabsorption and cerebral dysfunction: a multivariate and comparative study of autistic children.

Review 4. Causes of infantile autism: some considerations from recent research.

1. Receptor inhibition by immunoglobulins: specific inhibition by autistic children, their relatives, and control subjects.

2. Childhood psychosis and urinary excretion of peptides and protein-associated peptide complexes.

3. Histaminergic system in brain disorders: lessons from the translational approach and future perspectives.

4. Altered expression of histamine signaling genes in autism spectrum disorder.