Literature DB >> 437921

Discrepant effects of interferon murine syngeneic ascites tumors and their solid metastasizing counterparts.

W Ryd, B Hagmar, E Lundgren, O Strannegård.   

Abstract

The effects of interferon on mice with syngeneic tumors growing either intraperitoneally or as solid tumors were analyzed. The same dose that depressed the growth of ascites tumors, enhanced growth and in one case metastasizability of the corresponding solid tumors. The possibility that this was due to some host reaction is discussed. It seems important to develop animal models for analyzing interferon effects before treatment is initiated in human tumor disease.

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Year:  1979        PMID: 437921     DOI: 10.1002/ijc.2910230319

Source DB:  PubMed          Journal:  Int J Cancer        ISSN: 0020-7136            Impact factor:   7.396


  5 in total

1.  Treatment of advanced renal cell cancer with recombinant interferon alpha as a single agent and in combination with medroxyprogesterone acetate. A randomized multicenter trial.

Authors:  F Porzsolt; D Messerer; R Hautmann; A Gottwald; H Sparwasser; K Stockamp; W Aulitzky; J G Moormann; K Schumacher; H Rasche
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553

2.  Isoprinosine delays the early appearance of autoimmunity in NZB/NZW F1 mice treated with interferon.

Authors:  D Sergiescu; I Cerutti; A Kahan; D Piatier; E Efthymiou
Journal:  Clin Exp Immunol       Date:  1981-01       Impact factor: 4.330

3.  Accelerated tumor development in interferon-treated B6.C-Hyal-1 a mice.

Authors:  J De Maeyer-Guignard; E Lauret; L Eusèbe; E De Maeyer
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-15       Impact factor: 11.205

4.  Effects of the interferon-inducer ABPP on colon cancer in rats; importance of tumor load and tumor site.

Authors:  A M Eggermont; R L Marquet; R W de Bruin; J Jeekel
Journal:  Cancer Immunol Immunother       Date:  1986       Impact factor: 6.968

Review 5.  Interferons in cancer immunoediting: sculpting metastasis and immunotherapy response.

Authors:  Michelle von Locquenghien; Catalina Rozalén; Toni Celià-Terrassa
Journal:  J Clin Invest       Date:  2021-01-04       Impact factor: 14.808

  5 in total

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