Literature DB >> 4374284

Effect of pharmacological blockade on lithium-induced water drinking.

T A Perumal, J P Rao.   

Abstract

Administration of lithium chloride (40 mg/kg i.p.) led to a significant increase in 24 h water intake of rats. Prior administration of propranolol and haloperidol blocked the effect of lithium while atropine failed to show such an effect. The dipsogenic effect of lithium is probably exerted through beta-adrenergic and dopaminergic pathways.

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Year:  1974        PMID： 4374284      PMCID： PMC1776823          DOI： 10.1111/j.1476-5381.1974.tb09639.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  3 in total

1.  Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

Authors:  B S Bunney; J R Walters; R H Roth; G K Aghajanian
Journal:  J Pharmacol Exp Ther       Date:  1973-06       Impact factor: 4.030

2.  Polydipsia induced by isoprenaline and by lithium: relation to kidneys and renin.

Authors:  Y Gutman; F Benzakein; P Livneh
Journal:  Eur J Pharmacol       Date:  1971 Nov-Dec       Impact factor: 4.432

Review 3.  Lithium.

Authors:  J M Davis; W E Fann
Journal:  Annu Rev Pharmacol       Date:  1971       Impact factor: 13.820
  3 in total
  1 in total

1.  Lithium-induced polydipsia: dependence on nigrostriatal dopamine pathway and relationship to changes in the renin-angiotensin system.

Authors:  R B Mailman
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530
  1 in total

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