Literature DB >> 4369271

The carcinogenic effects of dimethylnitrosamine and nitrosomethylurea in European hamsters (Cricetus cricetus L.).

U Mohr, H Haas, J Hilfrich.   

Abstract

The carcinogenic effects of dimethylnitrosamine (DMN) and nitrosomethylurea (NMU) injected subcutaneously at 3 different dose levels in European hamsters were studied. DMN induced malignant haemangioendotheliomata of the liver and kidney, hepatocellular carcinomata and, in one animal, a cholangiocellular carcinoma. The effect of NMU was localized at the site of administration and resulted in subcutaneous fibrosarcomata, carcinosarcomata or epidermal carcinomata.

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Year:  1974        PMID: 4369271      PMCID: PMC2009008          DOI: 10.1038/bjc.1974.83

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  6 in total

1.  MALIGNANT TUMORS INDUCED IN MICE FED WITH N-NITROSODIMETHYLAMINE.

Authors:  S TAKAYAMA; K OOTA
Journal:  Gan       Date:  1963-12

2.  CARCINOGENESIS STUDY WITH DIMETHYLNITROSAMINE ADMINISTERED ORALLY TO ADULT AND SUBCUTANEOUSLY TO NEWBORN BALB-C MICE.

Authors:  B TOTH; P N MAGEE; P SHUBIK
Journal:  Cancer Res       Date:  1964-11       Impact factor: 12.701

3.  [Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

Authors:  H Druckrey; R Preussmann; S Ivankovic; D Schmähl
Journal:  Z Krebsforsch       Date:  1967

4.  Comparative studies with different doses of N-nitrosomorpholine, N-nitrosopiperidine, N-nitrosomethylurea, and dimethylnitrosamine in Syrian golden hamsters.

Authors:  H Haas; U Mohr; F W Krüger
Journal:  J Natl Cancer Inst       Date:  1973-10       Impact factor: 13.506

5.  Vascular tumors in female mice after intraperitoneal injection of dimethylnitrosamine.

Authors:  A Cardesa; P Pour; J Althoff; U Mohr
Journal:  J Natl Cancer Inst       Date:  1973-07       Impact factor: 13.506

6.  Ultrastructural analysis of renal mesenchymal tumor induced in the rat by dimethylnitrosamine.

Authors:  G C Hard; W H Butler
Journal:  Cancer Res       Date:  1971-03       Impact factor: 12.701

  6 in total
  2 in total

1.  Comparative study on the carcinogenicity of N-nitroso-2,6-dimethylmorpholine in the European hamster.

Authors:  J Althoff; U Mohr; W Lijinsky
Journal:  J Cancer Res Clin Oncol       Date:  1985       Impact factor: 4.553

2.  Carcinogenic effects of different nitroso-compounds in Chinese hamsters. I. Dimethylnitrosamine and N-diethylnitrosamine.

Authors:  G Reznik; U Mohr; N Kmoch
Journal:  Br J Cancer       Date:  1976-04       Impact factor: 7.640

  2 in total

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