Literature DB >> 4367223

A study of foot-and-mouth disease virus strains by complement fixation. I. A model for the fixation of complement by antigen-antibody mixtures.

A J Forman.   

Abstract

An examination was made of the relations between antigen, antibody and fixation of complement with foot-and-mouth disease virus (FMDV). It was found that complement fixation in this system follows the same principles as models developed in other antigen/antibody systems. The assumption that there is a relation of direct proportionality between the amount of complement fixed and the amount of antiserum reacting with constant antigen was found to be incorrect. An alternative method was proposed for the quantitative differentiation of FMDV strains by comparing the titres of an antiserum when reacting with optimum amounts of homologous or heterologous antigens.

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Year:  1974        PMID: 4367223      PMCID: PMC2130536          DOI: 10.1017/s0022172400023639

Source DB:  PubMed          Journal:  J Hyg (Lond)        ISSN: 0022-1724


  9 in total

1.  PURIFICATION OF RADIOACTIVE FOOT-AND-MOUTH DISEASE VIRUS.

Authors:  F BROWN; B CARTWRIGHT
Journal:  Nature       Date:  1963-09-21       Impact factor: 49.962

2.  A COMPLEMENT FIXATION TECHNIQUE FOR THE QUANTITATIVE MEASUREMENT OF ANTIGENIC DIFFERENCES BETWEEN STRAINS OF THE VIRUS OF FOOT-AND-MOUTH DISEASE.

Authors:  J DAVIE
Journal:  J Hyg (Lond)       Date:  1964-12

3.  The differentiation of subtypes (variants) of foot-and-mouth disease virus by serologic methods. I. Complement-fixation test.

Authors:  J H GRAVES
Journal:  Am J Vet Res       Date:  1960-07       Impact factor: 1.156

4.  The complement-fixation test in studies of components of the virus system of foot-and-mouth disease and its antibodies.

Authors:  C J BRADISH; J B BROOKSBY; H TSUBAHARA
Journal:  J Gen Microbiol       Date:  1960-04

5.  Immunoreactions involving platelets. I. A steric and kinetic model for formation of a complex from a human antibody, quinidine as a haptene, and platelets; and for fixation of complement by the complex.

Authors:  N R SHULMAN
Journal:  J Exp Med       Date:  1958-05-01       Impact factor: 14.307

6.  Quantitative studies of complement fixation. V. Estimation of complement-fixing potency of immune sera and its relation to antibody-nitrogen content.

Authors:  A L WALLACE; A G OSLER; M M MAYER
Journal:  J Immunol       Date:  1950-12       Impact factor: 5.422

7.  Principles governing the practical application of complement-fixation tests.

Authors:  J O DE ALMEIDA; A M SILVERSTEIN; F MALTANER
Journal:  J Immunol       Date:  1952-05       Impact factor: 5.422

8.  A study of foot-and-mouth disease virus strains by complement fixation. II. A comparison of tube and microplate tests for the differentiation of strains.

Authors:  A J Forman
Journal:  J Hyg (Lond)       Date:  1974-06

9.  Comparative complement-fixation studies with subtype strains of foot-and-mouth disease virus.

Authors:  J H Darbyshire; R S Hedger; E M Arrowsmith
Journal:  J Hyg (Lond)       Date:  1972-03
  9 in total
  5 in total

1.  The sub-type classification of strains of foot-and-mouth disease virus.

Authors:  A J Forman
Journal:  J Hyg (Lond)       Date:  1975-04

2.  Milk whey as a serum supplement for the growth of FMD virus in BHK-21 cells.

Authors:  S N Saha; A K Sen
Journal:  Vet Res Commun       Date:  1989       Impact factor: 2.459

3.  Microneutralization tests for serological typing and subtyping of foot-and-mouth disease virus strains.

Authors:  M M Rweyemamu; J C Booth; M Head; T W Pay
Journal:  J Hyg (Lond)       Date:  1978-08

4.  A study of foot-and-mouth disease virus strains by complement fixation. II. A comparison of tube and microplate tests for the differentiation of strains.

Authors:  A J Forman
Journal:  J Hyg (Lond)       Date:  1974-06

5.  Neutralization kinetics studies with type SAT 2 foot-and-mouth disease virus strains.

Authors:  M M Rweyemamu; J C Booth; N Parry; T W Pay
Journal:  J Hyg (Lond)       Date:  1977-06
  5 in total

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